| Also known as: |
IL2RA / CD25 |
| Other names: |
CD_antigen: CD25, IL-2 receptor subunit alpha, IL-2R subunit alpha, Interleukin-2 receptor subunit alpha, TAC antigen, TAC antigen, alpha, interleukin 2 receptor, interleukin-2 receptor subunit alpha, p55, interleukin-2 receptor subunit alpha |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
IL2RA |
| Gene name synonims: |
CD25 |
| Other gene names: |
CD25, IDDM10, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, IL2R, IL2RA, TCGFR, p55, IL2RA |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human IL-2Ralpha |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
Lyophilized from PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Aliquot and freeze the antibody should be stored at -20 degrees Celsius, Avoid freeze/thaw cycles, Reconstituted for up to two weeks at the antibodys should be kept in the range of 1-7 degrees Celsius, for long term storage, Store Lyophilized at room temperature up to 1 month |
| Tested applications:: |
ELISA (EIA), IHC - Frozen), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG2a, k) IL2RA / CD25 |
| Short name: |
Mouse Monoclonal (IgG2a, k) IL2RA / CD25 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
alpha / CD25 (Antibody to), sapiens interleukin 2 receptor, Mouse monoclonal (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD25 and IDDM10 and IL2R and p55 and TCGFR, Cell surfaces, IL2RA and IDBG-50566 and ENSG00000134460 and 3559, IL2RA and IDBG-637067 and ENSBTAG00000020892 and 281861, Il2ra and IDBG-136654 and ENSMUSG00000026770 and 16184, alpha, interleukin-2 binding, this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0004911 and interleukin-2 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006924 and activation-induced cell death of T cells and biological process this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008144 and drug binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019976 and interleukin-2 binding and molecular function this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046013 and regulation of T cell homeostatic proliferation and biological process this GO :0050672 and negative regulation of lymphocyte proliferation and biological process this GO :0050687 and negative regulation of defense response to virus and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050777 and negative regulation of immune response and biological process, this GO :0004911 : interleukin-2 receptor activity, this GO :0004911 : interleukin-2 receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0019976 : interleukin-2 binding, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0019976 : interleukin-2 binding, interleukin 2 receptor |
| Identity: |
6008 |
| Gene: |
IL2RA |
More about : IL2RA |
| Long gene name: |
interleukin 2 receptor subunit alpha |
| Synonyms gene: |
IL2R IDDM10 |
| Synonyms gene name: |
alpha , insulin-dependent diabetes mellitus 10 interleukin 2 receptor |
| Synonyms: |
CD25 |
| Locus: |
10p15, 1 |
| Discovery year: |
1990-01-22 |
| GenBank acession: |
X01057 |
| Entrez gene record: |
3559 |
| Pubmed identfication: |
3925551 17676041 |
| RefSeq identity: |
NM_000417 |
| Classification: |
Sushi domain containing CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000017616 |
| Locus Specific Databases: |
IL2RAbase: Mutation registry for Interleuken 2 receptor &, deficiency LRG_73 , #945 |