| Also known as: |
IL8 |
| Other names: |
C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, Emoctakin, GCP-1, Granulocyte chemotactic protein 1, IL8/NAP1 form I, Interleukin-8, MDNCF, MONAP, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, NAP-1, Neutrophil-activating protein 1, Protein 3-10C, T-cell chemotactic factor, T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-aAlternative name(s):GCP/IL-8 protein IV, alveolar macrophage chemotactic factor I, beta endothelial cell-derived neutrophil activating peptide, beta-thromboglobulin-like protein, chemokine (C-X-C motif) ligand 8, emoctakin, granulocyte chemotactic protein 1, interleukin 8, interleukin-8, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, member 8, monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, neutrophil-activating peptide 1, small inducible cytokine subfamily B, tumor necrosis factor-induced gene 1, interleukin-8 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
IL8 |
| Other gene names: |
CXCL8, GCP-1, GCP-1, GCP1, IL-8, IL8, IL8, LECT, LUCT, LYNAP, LYNAP, MDNCF, MDNCF, MONAP, MONAP, NAF, NAF, NAP-1, NAP-1, NAP1, CXCL8 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
5D8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Anti-IL8 recognizes recombinant protein IL8 |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, pH 7, 02% Proclin 300, Citrate-Tris-HCl buffer |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| Gene: |
CXCL8 |
More about : CXCL8 |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 5D8] (IgG1) IL8 |
| Short name: |
Mouse Monoclonal [clone 5D8] (IgG1) IL8 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens interleukin 8 (Antibody to), Mouse monoclonal [clonality 5D8] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828, chemokine activity, this GO :0001525 and angiogenesis and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0005153 and interleukin-8 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031623 and receptor internalization and biological process this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042119 and neutrophil activation and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0045087 and innate immune response and biological process this GO :0045091 and regulation of retroviral genome replication and biological process this GO :0045744 and negative regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0048566 and embryonic digestive tract development and biological process this GO :0050930 and induction of positive chemotaxis and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process, this GO :0005153 : interleukin-8 receptor binding, this GO :0005153 : interleukin-8 receptor binding and also this GO :0005515 : protein binding and also this GO :0008009 : chemokine activity, this GO :0005515 : protein binding, this GO :0008009 : chemokine activity, interleukin 8 |
| Identity: |
6025 |
| Long gene name: |
C-X-C motif chemokine ligand 8 |
| Synonyms gene: |
IL8 |
| Synonyms gene name: |
interleukin 8 chemokine (C-X-C motif) ligand 8 |
| Synonyms: |
SCYB8 LUCT LECT MDNCF TSG-1 IL-8 NAP-1 3-10C MONAP AMCF-I LYNAP NAF b-ENAP GCP-1 K60 GCP1 NAP1 |
| Synonyms name: |
neutrophil-activating peptide 1 granulocyte chemotactic protein 1 monocyte-derived neutrophil chemotactic factor lung giant cell carcinoma-derived chemotactic protein tumor necrosis factor-induced gene 1 monocyte-derived neutrophil-activating peptide lymphocyte derived neutrophil activating peptide beta endothelial cell-derived neutrophil activating peptide alveolar macrophage chemotactic factor I |
| Locus: |
4q13, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
Y00787 |
| Entrez gene record: |
3576 |
| Pubmed identfication: |
1427896 11178128 |
| RefSeq identity: |
NM_000584 |
| Classification: |
Endogenous ligands Chemokine ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000151316 |