| Also known as: |
FOLH1 / PSMA |
| Other names: |
Cell growth-inhibiting gene 27 protein, FGCP, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, GCPII, Glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated alpha-linked acidic dipeptidase 1, N-acetylated-alpha-linked acidic dipeptidase I, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, NAALADase I, PSM, PSMA, Prostate-specific membrane antigen, Pteroylpoly-gamma-glutamate carboxypeptidase, cell growth-inhibiting gene 27 protein, folate hydrolase (prostate-specific membrane antigen) 1, folylpoly-gamma-glutamate carboxypeptidase, glutamate carboxylase II, glutamate carboxypeptidase 2, glutamate carboxypeptidase II, mGCP, membrane glutamate carboxypeptidase, prostate specific membrane antigen variant F, pteroylpoly-gamma-glutamate carboxypeptidase, glutamate carboxypeptidase 2 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
FOLH1 |
| Gene name synonims: |
PSMA |
| Other gene names: |
FGCP, FGCP, FOLH, FOLH, FOLH1, GCP2, GCPII, GCPII, NAALAD1, NAALAD1, NAALADase I, NAALAdase, PSM, PSM, PSM, PSMA, PSMA, PSMA, mGCP, mGCP, FOLH1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b, k |
| Clone: |
Y-PSMA2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Little or no cross-reactivity to benign prostate hyperplasia (BPH) or to normal prostatic tissue, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recognizes human PSMA expressed LNCap cell lines |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
pH 7, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), IHC - Frozen), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ Y-PSMA2] (IgG2b, k) FOLH1 / PSMA |
| Short name: |
Mouse Monoclonal [clone Y-PSMA2] (IgG2b, k) FOLH1 / PSMA Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
2] (IgG2b, a classification, macropain) subunit, sapiens FOLH1 / PSMA (Antibody to), Mouse monoclonal [clonality Y-proteasome (prosome, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
2, PSMA2 and IDBG-13609 and ENSG00000106588 and 5683, TAP-dependent and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004298 and threonine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005839 and proteasome core complex and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, alpha type, alpha-subunit complex and cellular component this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, macropain) subunit, nuclei, protein binding, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0009615 and response to virus and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0019773 and proteasome core complex, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0000932 and cytoplasmic mRNA processing body and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004298 : threonine-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0004298 : threonine-type endopeptidase activity, this GO :0005515 : protein binding, proteasome (prosome |
| Identity: |
3788 |
| Gene: |
FOLH1 |
More about : FOLH1 |
| Long gene name: |
folate hydrolase 1 |
| Synonyms gene: |
FOLH |
| Synonyms gene name: |
folate hydrolase (prostate-specific membrane antigen) 1 |
| Synonyms: |
PSM PSMA NAALAD1 NAALAdase GCP2 GCPII |
| Synonyms name: |
glutamate carboxylase II glutamate carboxypeptidase 2 |
| Locus: |
11p11, 12 |
| Discovery year: |
1996-12-16 |
| GenBank acession: |
M99487 |
| Entrez gene record: |
2346 |
| Pubmed identfication: |
9838072 |
| RefSeq identity: |
NM_004476 |
| Havana BLAST/BLAT: |
OTTHUMG00000166625 |