| Also known as: |
LMNA / Lamin A/C |
| Other names: |
70 kDa lamin, 70 kDa lamin, Prelamin-A/C, Renal carcinoma antigen NY-REN-32, lamin, lamin A/C, lamin A/C-like 1, prelamin-A/C, renal carcinoma antigen NY-REN-32, lamin isoform C |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
LMNA |
| Other gene names: |
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMN1, LMNA, LMNC, LMNL1, PRO1, LMNA |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
JOL2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
It has been shown to bind to an epitope between amino acids 464-572, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, The antibody reacts with both recombinant and native Lamin A and C in humans |
| Purification method: |
Tissue culture supernatant |
| Form/Appearance: |
0, 5-10% fetal calf serum, Sourced in TCS, pH 7, 2 M Tris/HCl, 4, Tissue culture supernatant |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ JOL2] (IgG1) LMNA / Lamin A/C |
| Short name: |
Mouse Monoclonal [clone JOL2] (IgG1) LMNA / Lamin A/C Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens LMNA / Lamin A/C (Antibody to), Mouse monoclonal [clonality JOL2] (IgG1) to H |
| Alternative technique: |
antibodies |
| Identity: |
6636 |
| Gene: |
LMNA |
More about : LMNA |
| Long gene name: |
lamin A/C |
| Synonyms gene: |
LMN1 CMD1A LGMD1B PRO1 LMNL1 |
| Synonyms gene name: |
cardiomyopathy, dilated 1A (autosomal dominant) limb girdle muscular dystrophy 1B (autosomal dominant) progeria 1 (Hutchinson-Gilford type) lamin A/C-like 1 |
| Synonyms: |
HGPS MADA |
| Synonyms name: |
mandibuloacral dysplasia type A |
| Locus: |
1q22 |
| Discovery year: |
1992-04-09 |
| GenBank acession: |
BC014507 |
| Entrez gene record: |
4000 |
| Pubmed identfication: |
8511676 8838815 12702809 |
| RefSeq identity: |
NM_170707 |
| Classification: |
Lamins |
| Havana BLAST/BLAT: |
OTTHUMG00000013961 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database Leiden Muscular Dystrophy Pages UMD Locus Specific Databases Leiden Muscular Dystrophy pages LRG_254 |