| Also known as: |
NPM1 / NPM / Nucleophosmin |
| Other names: |
Nucleolar phosphoprotein B23, Nucleolar protein NO38, Nucleophosmin, Numatrin, member 1, nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, nucleophosmin/nucleoplasmin family, numatrin), nucleophosmin isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
NPM1 |
| Other gene names: |
B23, NPM, NPM, NPM, NPM1, NPM1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b, k |
| Clone: |
5000 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, pH 7, 1% sodium azide, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 5E3] (IgG2b, k) NPM1 / NPM / Nucleophosmin |
| Short name: |
Mouse Monoclonal [clone 5E3] (IgG2b, k) NPM1 / NPM / Nucleophosmin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
numatrin) / NPM / Nucleophosmin (Antibody to), sapiens nucleophosmin (nucleolar phosphoprotein B23, Mouse monoclonal [clonality 5E3] (IgG2b, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
B23 and NPM, NPM1 and IDBG-57453 and ENSG00000181163 and 4869, nuclei, numatrin), this GO :0003676 and nucleic acid binding and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0003723 and RNA binding and molecular function this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006281 and DNA repair and biological process this GO :0006334 and nucleosome assembly and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0006950 and response to stress and biological process this GO :0007098 and centrosome cycle and biological process this GO :0007165 and signal transduction and biological process this GO :0007569 and cell aging and biological process this GO :0008104 and protein localization and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010826 and negative regulation of centrosome duplication and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030529 and ribonucleoprotein complex and cellular component this GO :0030957 and Tat protein binding and molecular function this GO :0031616 and spindle pole centrosome and cellular component this GO :0032071 and regulation of endodeoxyribonuclease activity and biological process this GO :0034080 and centromere-specific nucleosome assembly and biological process this GO :0042255 and ribosome assembly and biological process this GO :0042393 and histone binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043023 and ribosomal large subunit binding and molecular function this GO :0043024 and ribosomal small subunit binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044387 and negative regulation of protein kinase activity by regulation of protein phosphorylation and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045727 and positive regulation of translation and biological process this GO :0046599 and regulation of centriole replication and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051059 and NF-kappaB binding and molecular function this GO :0051082 and unfolded protein binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0060699 and regulation of endoribonuclease activity and biological process this GO :0060735 and regulation of eIF2 alpha phosphorylation by dsRNA and biological process, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0003713 : transcription coactivator activity and also this GO :0003723 : RNA binding and also this GO :0004860 : protein kinase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0030957 : Tat protein binding and also this GO :0042393 : histone binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043023 : ribosomal large subunit binding and also this GO :0043024 : ribosomal small subunit binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0051059 : NF-kappaB binding and also this GO :0051082 : unfolded protein binding, this GO :0003713 : transcription coactivator activity, this GO :0003723 : RNA binding, this GO :0004860 : protein kinase inhibitor activity, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0030957 : Tat protein binding, this GO :0042393 : histone binding, this GO :0042803 : protein homodimerization activity, this GO :0043023 : ribosomal large subunit binding, this GO :0043024 : ribosomal small subunit binding, this GO :0044822 : poly(A) RNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0051059 : NF-kappaB binding, this GO :0051082 : unfolded protein binding, unfolded protein binding, nucleophosmin (nucleolar phosphoprotein B23 |
| Identity: |
7910 |
| Gene: |
NPM1 |
More about : NPM1 |
| Long gene name: |
nucleophosmin |
| Synonyms gene name: |
nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
| Synonyms: |
B23 NPM |
| Synonyms name: |
member 1 , nucleolar phosphoprotein B23 numatrin nucleophosmin/nucleoplasmin family |
| Locus: |
5q35, 1 |
| Discovery year: |
1993-08-24 |
| GenBank acession: |
M26697 |
| Entrez gene record: |
4869 |
| Pubmed identfication: |
8471164 8122112 |
| RefSeq identity: |
NM_002520 |
| Havana BLAST/BLAT: |
OTTHUMG00000130465 |
| Locus Specific Databases: |
LRG_458 |