| Also known as: |
PTGS2 / COX2 / COX-2 |
| Other names: |
COX-2, Cyclooxygenase-2, PGH synthase 2, PGH synthase 2, PGHS-2, PHS II, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, cyclooxygenase 2b, prostaglandin G/H synthase 2, prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), prostaglandin G/H synthase 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PTGS2 |
| Gene name synonims: |
COX-2, COX2 |
| Other gene names: |
COX-2, COX-2, COX2, COX2, GRIPGHS, PGG/HS, PGH synthase 2, PGHS-2, PGHS-2, PHS-2, PTGS2, hCox-2, PTGS2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
COX 229 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recognizes human COX-2 |
| Purification method: |
Purified |
| Form/Appearance: |
0, 1% BSA, pH 7, 1% sodium azide, 4, PBS |
| Concentration: |
18 mg/ml |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
IHC - Frozen), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ COX 229] (IgG1, k) PTGS2 / COX2 / COX-2 |
| Short name: |
Mouse Monoclonal [clone COX 229] (IgG1, k) PTGS2 / COX2 / COX-2 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) / COX2 / COX-2 (Antibody to), Mouse monoclonal [clonality COX 229] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
COX-2 and COX2 and GRIPGHS and hCox-2 and PGG/HS and PGHS-2 and PHS-2, PGHS-2 and IDBG-637781 and ENSBTAG00000014127 and 282023, PTGS2 and IDBG-105426 and ENSG00000073756 and 5743, Ptgs2 and IDBG-197327 and ENSMUSG00000032487 and 19225, acting on single donors with incorporation of molecular oxygen, acting on single donors with incorporation of molecular oxygen, acting on single donors with incorporation of molecular oxygen, dopaminergic and biological process this GO :0032355 and response to estradiol and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033280 and response to vitamin D and biological process this GO :0034097 and response to cytokine and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0034644 and cellular response to UV and biological process this GO :0035633 and maintenance of blood-brain barrier and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042493 and response to drug and biological process this GO :0042633 and hair cycle and biological process this GO :0042640 and anagen and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0045987 and positive regulation of smooth muscle contraction and biological process this GO :0046697 and decidualization and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0050473 and arachidonate 15-lipoxygenase activity and molecular function this GO :0050727 and regulation of inflammatory response and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051926 and negative regulation of calcium ion transport and biological process this GO :0051968 and positive regulation of synaptic transmission, glutamatergic and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070542 and response to fatty acid and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071318 and cellular response to ATP and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071636 and positive regulation of transforming growth factor beta production and biological process this GO :0090050 and positive regulation of cell migration involved in sprouting angiogenesis and biological process this GO :0090271 and positive regulation of fibroblast growth factor production and biological process this GO :0090336 and positive regulation of brown fat cell differentiation and biological process this GO :0090362 and positive regulation of platelet-derived growth factor production and biological process, incorporation of two atoms of oxygen, incorporation of two atoms of oxygen and also this GO :0019899 : enzyme binding and also this GO :0020037 : heme binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding and also this GO :0050473 : arachidonate 15-lipoxygenase activity, incorporation of two atoms of oxygen and molecular function this GO :0019233 and sensory perception of pain and biological process this GO :0019369 and arachidonic acid metabolic process and biological process this GO :0019371 and cyclooxygenase pathway and biological process this GO :0019372 and lipoxygenase pathway and biological process this GO :0019899 and enzyme binding and molecular function this GO :0020037 and heme binding and molecular function this GO :0030282 and bone mineralization and biological process this GO :0030728 and ovulation and biological process this GO :0031394 and positive regulation of prostaglandin biosynthetic process and biological process this GO :0031622 and positive regulation of fever generation and biological process this GO :0031915 and positive regulation of synaptic plasticity and biological process this GO :0032227 and negative regulation of synaptic transmission, nuclei, oxidoreductase activity, this GO :0001516 and prostaglandin biosynthetic process and biological process this GO :0001525 and angiogenesis and biological process this GO :0004601 and peroxidase activity and molecular function this GO :0004666 and prostaglandin-endoperoxide synthase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006693 and prostaglandin metabolic process and biological process this GO :0006928 and cellular component movement and biological process this GO :0006954 and inflammatory response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007566 and embryo implantation and biological process this GO :0007612 and learning and biological process this GO :0007613 and memory and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008289 and lipid binding and molecular function this GO :0009314 and response to radiation and biological process this GO :0009750 and response to fructose and biological process this GO :0010033 and response to organic substance and biological process this GO :0010042 and response to manganese ion and biological process this GO :0010226 and response to lithium ion and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010575 and positive regulation vascular endothelial growth factor production and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016702 and oxidoreductase activity, this GO :0004601 : peroxidase activity, this GO :0004601 : peroxidase activity and also this GO :0004666 : prostaglandin-endoperoxide synthase activity and also this GO :0005515 : protein binding and also this GO :0008289 : lipid binding and also this GO :0016702 : oxidoreductase activity, this GO :0004666 : prostaglandin-endoperoxide synthase activity, this GO :0005515 : protein binding, this GO :0008289 : lipid binding, this GO :0016702 : oxidoreductase activity, this GO :0019899 : enzyme binding, this GO :0020037 : heme binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, this GO :0050473 : arachidonate 15-lipoxygenase activity, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| Identity: |
9605 |
| Gene: |
PTGS2 |
More about : PTGS2 |
| Long gene name: |
prostaglandin-endoperoxide synthase 2 |
| Synonyms gene name: |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| Synonyms: |
COX2 |
| Synonyms name: |
prostaglandin G/H synthase 2 cyclooxygenase 2 |
| Locus: |
1q31, 1 |
| Discovery year: |
1992-10-28 |
| GenBank acession: |
D28235 |
| Entrez gene record: |
5743 |
| Pubmed identfication: |
1380156 |
| RefSeq identity: |
NM_000963 |
| Havana BLAST/BLAT: |
OTTHUMG00000035473 |