| Also known as: |
DIABLO / SMAC |
| Other names: |
Diablo homolog, Direct IAP-binding protein with low pI, IAP-binding mitochondrial protein, Second mitochondria-derived activator of caspase, Smac, diablo, diablo homolog, direct IAP-binding protein with low pI, mitochondrial, mitochondrial, mitochondrial isoform 1, second mitochondria-derived activator of caspase, diablo homolog |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
DIABLO |
| Gene name synonims: |
SMAC |
| Other gene names: |
DFNA64, DIABLO, SMAC, SMAC, Smac, DIABLO |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
79-1-83 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Monkey, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human and monkey Smac/DIABLO |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 50% glycerol, pH 7, 09% azide, 2, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 79-1-83] (IgG2b) DIABLO / SMAC |
| Short name: |
Mouse Monoclonal [clone 79-1-83] (IgG2b) DIABLO / SMAC Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
IAP-binding mitochondrial protein / SMAC (Antibody to), sapiens diablo, Mouse monoclonal [clonality 79-1-83] (IgG2b) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DIABLO and IDBG-62263 and ENSG00000184047 and 56616, DIABLO and IDBG-632769 and ENSBTAG00000004199 and 493999, Diablo and IDBG-199693 and ENSMUSG00000029433 and 66593, IAP-binding mitochondrial protein, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0035631 and CD40 receptor complex and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, diablo |
| Identity: |
21528 |
| Gene: |
DIABLO |
More about : DIABLO |
| Long gene name: |
diablo IAP-binding mitochondrial protein |
| Synonyms gene name: |
IAP-binding mitochondrial protein , diablo |
| Synonyms: |
SMAC DIABLO-S FLJ25049 FLJ10537 DFNA64 |
| Synonyms name: |
second mitochondria-derived activator of caspase |
| Locus: |
12q24, 31 |
| Discovery year: |
2003-10-27 |
| GenBank acession: |
AF262240 |
| Entrez gene record: |
56616 |
| Pubmed identfication: |
12749848 17237824 21722859 |
| RefSeq identity: |
NM_019887 |
| Classification: |
Deafness associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000157014 |