| Also known as: |
ICAM1 / CD54 |
| Other names: |
CD_antigen: CD54, ICAM-1, Intercellular adhesion molecule 1, Major group rhinovirus receptor, cell surface glycoprotein P3, human rhinovirus receptor, intercellular adhesion molecule 1, intercellular adhesion molecule 1, intercellular adhesion molecule 1 (CD54), major group rhinovirus receptor, 58, intercellular adhesion molecule 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ICAM1 |
| Gene name synonims: |
CD54 |
| Other gene names: |
BB2, CD54, ICAM-1, ICAM1, P3, 58, ICAM1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2, 15 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Pig, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD54 is expressed by many cells following activation by inflammatory mediators, Clone 15, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 90kD glycoprotein also known as ICAM-1, 2 is reported to block CD54 function, Recognizes the human CD54 cell surface antigen |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 09% sodium azide, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS), IHC - Frozen), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
2] (IgG1) ICAM1 / CD54, Monoclonal [ 15 |
| Short name: |
2] (IgG1) ICAM1 / CD54 Antibody, Mouse Monoclonal [clone 15 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens intercellular adhesion molecule 1 / CD54 (Antibody to), 2] (IgG1) to H, Mouse monoclonal [clonality 15 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BB2 and CD54 and P3, Extracellular, ICAM1 and IDBG-26804 and ENSG00000090339 and 3383, ICAM1 and IDBG-643247 and ENSBTAG00000010303 and 281839, Icam1 and IDBG-138668 and ENSMUSG00000037405 and 15894, protein complex binding, this GO :0001541 and ovarian follicle development and biological process this GO :0001618 and virus receptor activity and molecular function this GO :0001666 and response to hypoxia and biological process this GO :0001772 and immunological synapse and cellular component this GO :0001910 and regulation of leukocyte mediated cytotoxicity and biological process this GO :0001975 and response to amphetamine and biological process this GO :0002291 and T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell and biological process this GO :0002438 and acute inflammatory response to antigenic stimulus and biological process this GO :0002457 and T cell antigen processing and presentation and biological process this GO :0002693 and positive regulation of cellular extravasation and biological process this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007569 and cell aging and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010212 and response to ionizing radiation and biological process this GO :0010477 and response to sulfur dioxide and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0022614 and membrane to membrane docking and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031669 and cellular response to nutrient levels and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033627 and cell adhesion mediated by integrin and biological process this GO :0034698 and response to this GO nadotropin and biological process this GO :0042493 and response to drug and biological process this GO :0043200 and response to amino acid and biological process this GO :0044406 and adhesion of symbiont to host and biological process this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0046688 and response to copper ion and biological process this GO :0046813 and receptor-mediated virion attachment to host cell and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051926 and negative regulation of calcium ion transport and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0061028 and establishment of endothelial barrier and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071310 and cellular response to organic substance and biological process this GO :0071312 and cellular response to alkaloid and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0097368 and establishment of Sertoli cell barrier and biological process this GO :1900027 and regulation of ruffle assembly and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding, this GO :0004872 : receptor activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0032403 : protein complex binding, 58, intercellular adhesion molecule 1 |
| Identity: |
5344 |
| Gene: |
ICAM1 |
More about : ICAM1 |
| Long gene name: |
intercellular adhesion molecule 1 |
| Synonyms: |
BB2 CD54 |
| Synonyms name: |
human rhinovirus receptor |
| Locus: |
19p13, 2 |
| Discovery year: |
1989-04-24 |
| Entrez gene record: |
3383 |
| Pubmed identfication: |
2453850 3871395 |
| Classification: |
Endogenous ligands CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180403 |