| Also known as: |
SORL1 |
| Other names: |
L(DLR class) A repeats containing, L(DLR class) A repeats-containing, LDLR relative with 11 ligand-binding repeats, LDLR relative with 11 ligand-binding repeats, LR11, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, SorLA, SorLA-1, Sortilin-related receptor, Sorting protein-related receptor containing LDLR class A repeats, low-density lipoprotein receptor relative with 11 ligand-binding repeats, mosaic protein LR11, sortilin-related receptor, sortilin-related receptor, sortilin-related receptor, sorting protein-related receptor containing LDLR class A repeats, sortilin-related receptor preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SORL1 |
| Other gene names: |
C11orf32, C11orf32, LDLR relative with 11 ligand-binding repeats, LR11, LR11, LRP9, SORL1, SORLA, SorLA, SorLA-1, gp250, SORL1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Purified truncated recombinant SORL1-MBP expressed in E Coli strain BL21 (DE3) |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 03% sodium azide, Ascites |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG1) SORL1 |
| Short name: |
Mouse Monoclonal (IgG1) SORL1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
L(DLR class) A repeats containing (Antibody to), sapiens sortilin-related receptor, Mouse monoclonal (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADP-ribosylation factor binding, C11orf32 and gp250 and LR11 and LRP9 and SORLA and SorLA-1, L(DLR class) A repeats containing, SORL1 and IDBG-632166 and ENSBTAG00000014611 and 533166, SORL1 and IDBG-74757 and ENSG00000137642 and 6653, Sorl1 and IDBG-154026 and ENSMUSG00000049313 and 20660, nuclei, this GO :0000042 and protein targeting to this GO lgi and biological process this GO :0001540 and beta-amyloid binding and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005641 and nuclear envelope lumen and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005771 and multivesicular body and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006605 and protein targeting and biological process this GO :0006622 and protein targeting to lysosome and biological process this GO :0006869 and lipid transport and biological process this GO :0006892 and post- this GO lgi vesicle-mediated transport and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008219 and cell death and biological process this GO :0008283 and cell proliferation and biological process this GO :0014910 and regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030306 and ADP-ribosylation factor binding and molecular function this GO :0031985 and this GO lgi cisterna and cellular component this GO :0032091 and negative regulation of protein binding and biological process this GO :0032460 and negative regulation of protein oli this GO merization and biological process this GO :0034362 and low-density lipoprotein particle and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0045053 and protein retention in this GO lgi apparatus and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0050768 and negative regulation of neurogenesis and biological process this GO :0051604 and protein maturation and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070863 and positive regulation of protein exit from endoplasmic reticulum and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :1902430 and negative regulation of beta-amyloid formation and biological process this GO :1902771 and positive regulation of choline O-acetyltransferase activity and biological process this GO :1902948 and negative regulation of tau-protein kinase activity and biological process this GO :1902953 and positive regulation of ER to this GO lgi vesicle-mediated transport and biological process this GO :1902955 and positive regulation of early endosome to recycling endosome transport and biological process this GO :1902960 and negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process and biological process this GO :1902963 and negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process and biological process this GO :1902966 and positive regulation of protein localization to early endosome and biological process this GO :1902997 and negative regulation of neurofibrillary tangle assembly and biological process this GO :2001137 and positive regulation of endocytic recycling and biological process, this GO :0001540 : beta-amyloid binding, this GO :0001540 : beta-amyloid binding and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0030169 : low-density lipoprotein particle binding and also this GO :0030306 : ADP-ribosylation factor binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0030169 : low-density lipoprotein particle binding, this GO :0030306 : ADP-ribosylation factor binding, sortilin-related receptor |
| Identity: |
11185 |
| Gene: |
SORL1 |
More about : SORL1 |
| Long gene name: |
sortilin related receptor 1 |
| Synonyms gene: |
C11orf32 |
| Synonyms gene name: |
L(DLR class) A repeats-containing , chromosome 11 open reading frame 32 sortilin-related receptor |
| Synonyms: |
gp250 LR11 LRP9 SorLA SorLA-1 |
| Synonyms name: |
LDLR relative with 11 ligand-binding repeats |
| Locus: |
11q24, 1 |
| Discovery year: |
1996-12-27 |
| GenBank acession: |
Y08110 |
| Entrez gene record: |
6653 |
| Pubmed identfication: |
9157966 8940146 |
| RefSeq identity: |
NM_003105 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166057 |