| Also known as: |
LRP1 / CD91 |
| Other names: |
A2MR, APOER, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, CD_antigen: CD91Cleaved into the following 3 chains:Low-density lipoprotein receptor-related protein 1 85 kDa subunit, LRP-1, LRP-515, LRP-85, LRPICD, Low-density lipoprotein receptor-related protein 1 515 kDa subunit, Low-density lipoprotein receptor-related protein 1 intracellular domain, Prolow-density lipoprotein receptor-related protein 1, TbetaR-V/LRP-1/IGFBP-3 receptor, alpha-2-macroglobulin receptor, apolipoprotein E receptor, low density lipoprotein receptor-related protein 1, prolow-density lipoprotein receptor-related protein 1, type V tgf-beta receptor, prolow-density lipoprotein receptor-related protein 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
LRP1 |
| Gene name synonims: |
CD91 |
| Other gene names: |
A2MR, A2MR, A2MR, APOER, APOER, APR, APR, CD91, IGFBP3R, LRP, LRP-1, LRP-515, LRP-85, LRP1, LRP1A, LRPICD, TGFBR5, LRP1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Recognizes an epitope in the extracellular region of the 500kD alpha chain, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a type I membrane protein which is also known as the alpha 2 macroglobulin receptor (alpha 2 MR), Recognizes human CD91 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
40% glycerol, No preservatives added, pH 7, 4, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FC/FACS), IHC - Frozen), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG1) LRP1 / CD91 |
| Short name: |
Mouse Monoclonal (IgG1) LRP1 / CD91 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens low density lipoprotein receptor-related protein 1 / CD91 (Antibody to), Mouse monoclonal (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
A2MR and APOER and APR and CD91 and IGFBP3R and LRP and LRP1A and TGFBR5, LRP1 and IDBG-42176 and ENSG00000123384 and 4035, LRP1 and IDBG-635332 and ENSBTAG00000010830 and 533894, Lrp1 and IDBG-195360 and ENSMUSG00000040249 and 16971, lipoprotein particle receptor binding, nuclei, this GO :0001523 and retinoid metabolic process and biological process this GO :0002020 and protease binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007568 and aging and biological process this GO :0007603 and phototransduction, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0004872 : receptor activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding and also this GO :0034185 : apolipoprotein binding and also this GO :0042954 : lipoprotein transporter activity and also this GO :0044822 : poly(A) RNA binding and also this GO :0070325 : lipoprotein particle receptor binding, this GO :0004872 : receptor activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0032403 : protein complex binding, this GO :0034185 : apolipoprotein binding, this GO :0042954 : lipoprotein transporter activity, this GO :0044822 : poly(A) RNA binding, this GO :0070325 : lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008283 and cell proliferation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030136 and clathrin-coated vesicle and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030425 and dendrite and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0032370 and positive regulation of lipid transport and biological process this GO :0032374 and regulation of cholesterol transport and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032429 and regulation of phospholipase A2 activity and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0035909 and aorta morphogenesis and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0042954 and lipoprotein transporter activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0051222 and positive regulation of protein transport and biological process this GO :0070325 and lipoprotein particle receptor binding and molecular function this GO :0097242 and beta-amyloid clearance and biological process this GO :2000587 and negative regulation of platelet-derived growth factor receptor-beta signaling pathway and biological process, low density lipoprotein receptor-related protein 1 |
| Identity: |
6692 |
| Gene: |
LRP1 |
More about : LRP1 |
| Long gene name: |
LDL receptor related protein 1 |
| Synonyms gene: |
APR A2MR |
| Synonyms gene name: |
alpha-2-macroglobulin receptor low density lipoprotein receptor-related protein 1 |
| Synonyms: |
LRP CD91 LRP1A APOER |
| Locus: |
12q13, 3 |
| Discovery year: |
1991-08-21 |
| GenBank acession: |
X13916 |
| Entrez gene record: |
4035 |
| Pubmed identfication: |
2548950 |
| RefSeq identity: |
NM_002332 |
| Classification: |
Low density lipoprotein receptors CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000044412 |