| Also known as: |
CD20 |
| Other names: |
B-lymphocyte antigen CD20, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, CD20 antigen, CD20 receptor, CD_antigen: CD20, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, leukocyte surface antigen Leu-16, member 1, membrane-spanning 4-domains, subfamily A, B-lymphocyte antigen CD20 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD20 |
| Gene name synonims: |
MS4A1 |
| Other gene names: |
B1, Bp35, CD20, CD20, CVID5, LEU-16, MS4A1, MS4A2, S7, MS4A1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgM |
| Clone: |
MEM-269 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 33-37 kD non-glycosylated membrane receptor with four transmembrane domains, and at low levels on peripheral blood T lymphocytes, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, Reacts with CD20 (Bp35) |
| Purification method: |
Hydrophobic interaction chromatography |
| Form/Appearance: |
15 mM sodium azide, approx, pH 7, 4, PBS |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, IgM is by far the physically largest antibody in the human circulatory system, Immunoglobulin M, It is the first antibody to appear in response to initial exposure to an antigen, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, is a basic , or , plasma, primarily , saliva, urine, , (Homo sapiens, B cells, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, IgM , antibody , for short, humans , ssp, that is produced by |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ MEM-269] CD20 |
| Short name: |
Mouse Monoclonal [clone MEM-269] (IgM) CD20 Antibody |
| Technique: |
IgMs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgM |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens CD20 (Antibody to), Mouse monoclonal [clonality MEM-269] (Immunoglobulin M) to H |
| Alternative technique: |
antibodies |
| Identity: |
7315 |
| Gene: |
MS4A1 |
More about : MS4A1 |
| Long gene name: |
membrane spanning 4-domains A1 |
| Synonyms gene: |
CD20 |
| Synonyms gene name: |
member 1 , membrane-spanning 4-domains, subfamily A |
| Synonyms: |
B1 Bp35 MS4A2 |
| Locus: |
11q12, 2 |
| Discovery year: |
1989-05-23 |
| GenBank acession: |
M27394 |
| Entrez gene record: |
931 |
| Pubmed identfication: |
2448768 |
| Classification: |
CD molecules Membrane spanning 4-domains |
| Havana BLAST/BLAT: |
OTTHUMG00000167614 |
| Locus Specific Databases: |
LRG_140 |