| Also known as: |
F2 / Prothrombin / Thrombin |
| Other names: |
Activation peptide fragment 2, Coagulation factor IICleaved into the following 4 chains:Activation peptide fragment 1, Prothrombin, Thrombin heavy chain, Thrombin light chain, coagulation factor II (thrombin), prepro-coagulation factor II, prothrombin, prothrombin B-chain, serine protease, prothrombin preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
F2 |
| Other gene names: |
F2, N/A, PT, RPRGL2, THPH1, F2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Inhibits clotting and prothrombin activation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, fragment 2, meizothrombin, prethrombin-1, Recognizes human Prothrombin |
| Purification method: |
Ion exchange Chromatography |
| Form/Appearance: |
ddH2O, Supplied as a liquid in 50% glycerol |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG2a) F2 / Prothrombin / Thrombin |
| Short name: |
Mouse Monoclonal (IgG2a) F2 / Prothrombin / Thrombin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens coagulation factor II (thrombin) / Prothrombin / Thrombin (Antibody to), Mouse monoclonal (IgG2a) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, F2 and IDBG-191373 and ENSMUSG00000027249 and 14061, F2 and IDBG-42048 and ENSG00000180210 and 2147, F2 and IDBG-637247 and ENSBTAG00000007148 and 280685, PT and RPRGL2 and THPH1, intrinsic pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008233 and peptidase activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009611 and response to wounding and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010544 and negative regulation of platelet activation and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0017187 and peptidyl-glutamic acid carboxylation and biological process this GO :0030168 and platelet activation and biological process this GO :0030193 and regulation of blood coagulation and biological process this GO :0030194 and positive regulation of blood coagulation and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0042730 and fibrinolysis and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0048712 and negative regulation of astrocyte differentiation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051281 and positive regulation of release of sequestered calcium ion into cytosol and biological process this GO :0051480 and cytosolic calcium ion homeostasis and biological process this GO :0051918 and negative regulation of fibrinolysis and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component this GO :1900738 and positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006953 and acute-phase response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007596 and blood coagulation and biological process this GO :0007597 and blood coagulation, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004252 : serine-type endopeptidase activity and also this GO :0005102 : receptor binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0008233 : peptidase activity and also this GO :0070053 : thrombospondin receptor activity, this GO :0004252 : serine-type endopeptidase activity, this GO :0005102 : receptor binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0008233 : peptidase activity, this GO :0070053 : thrombospondin receptor activity, thrombospondin receptor activity, coagulation factor II (thrombin) |