| Also known as: |
C4BP / C4b-Binding Protein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
C4BP |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
42284 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S, C4bp also regulates the C4bC2a complex (C3 convertase), C4bp is expressed in the blood serum, C4bp regulates the activation of the classical complement pathway, It is a cofactor to the C3b/C4b inactivator, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The other complexes formed are a 530 kD homoheptamer of alpha chains or a 500 kD complex of 6 alpha chains and 1 beta chain, The predominant form is a 570 kD complex of 7 alpha chains and 1 beta chain, There are three variants of C4bp, This particular antibody might cross react with speacies outside of the listed ones, accelerating its degradation by dissociating the complement fragment C2a, composed of alpha and beta chains, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b, Recognizes complement component 4 binding protein (C4bp) |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
0, Sourced in Ascites, pH 8, 02% sodium azide, 4, Borate buffered saline |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freeze/thaw may reduce the activity, For longer periods of time, Store the antibodies in an undiluted form, freeze the antibody and keep it at -20 degrees Celsius, Keep the antibody refrigerated at +4 degrees Celsius for short periods of time |
| Tested applications:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 10-07] (IgG2b) C4BP / C4b-Binding Protein |
| Short name: |
Mouse Monoclonal [clone 10-07] (IgG2b) C4BP / C4b-Binding Protein Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens C4BP / complement component 4B (Chido blood group)-Binding Protein (Antibody to), Mouse monoclonal [clonality 10-07] (IgG2b) to H |
| Alternative technique: |
antibodies |
| Identity: |
1328 |
| Gene: |
C4BPB |
More about : C4BPB |
| Long gene name: |
complement component 4 binding protein beta |
| Synonyms gene: |
C4BP |
| Synonyms gene name: |
beta , complement component 4-binding protein |
| Synonyms name: |
beta chain , beta chain C4b binding protein, complement component 4 binding protein |
| Locus: |
1q32, 1 |
| Discovery year: |
1990-06-13 |
| GenBank acession: |
L11245 |
| Entrez gene record: |
725 |
| Pubmed identfication: |
2300577 8325877 |
| RefSeq identity: |
NM_000716 |
| Classification: |
Sushi domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000036035 |