| Also known as: |
TRAP / TRAF2 |
| Other names: |
E3 ubiquitin-protein ligase TRAF2, E3 ubiquitin-protein ligase TRAF2, TNF receptor-associated factor 2, TNF receptor-associated factor 2, TNF receptor-associated factor 2, Tumor necrosis factor type 2 receptor-associated protein 3, tumor necrosis factor type 2 receptor associated protein 3, tumor necrosis factor type 2 receptor-associated protein 3, TNF receptor-associated factor 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TRAP |
| Gene name synonims: |
TRAF2 |
| Other gene names: |
MGC:45012, TRAF2, TRAP, TRAP3, TRAP3, TRAF2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
33A1293  |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, A fusion protein corresponding to amino acids 205 to 222 of human TRAF2 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 0, 05% sodium azide, 2% gelatin, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum  |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 33A1293] TRAP / TRAF2 |
| Short name: |
Mouse Monoclonal [clone 33A1293] (IgG) TRAP / TRAF2 Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens TRAP / tumor necrosis factor receptor-associated factor 2 (Antibody to), Mouse monoclonal [clonality 33A1293] (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
MGC:45012 and TRAP and TRAP3, Plasma membranes, TRAF2 and IDBG-641438 and ENSBTAG00000010497 and 512355, TRAF2 and IDBG-92817 and ENSG00000127191 and 7186, Traf2 and IDBG-146254 and ENSMUSG00000026942 and 22030, metal ion binding, this GO :0002726 and positive regulation of T cell cytokine production and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005174 and CD40 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0016874 and ligase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0030163 and protein catabolic process and biological process this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0032403 and protein complex binding and molecular function this GO :0032743 and positive regulation of interleukin-2 production and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0034351 and negative regulation of glial cell apoptotic process and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0043623 and cellular protein complex assembly and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0046328 and regulation of JNK cascade and biological process this GO :0046625 and sphin this GO lipid binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051865 and protein autoubiquitination and biological process this GO :0070207 and protein homotrimerization and biological process this GO :0070534 and protein K63-linked ubiquitination and biological process this GO :0071732 and cellular response to nitric oxide and biological process this GO :0090073 and positive regulation of protein homodimerization activity and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097300 and programmed necrotic cell death and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0004871 : signal transducer activity and also this GO :0005102 : receptor binding and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005174 : CD40 receptor binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0019899 : enzyme binding and also this GO :0019903 : protein phosphatase binding and also this GO :0031435 : mitogen-activated protein kinase kinase kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding and also this GO :0032403 : protein complex binding and also this GO :0042802 : identical protein binding and also this GO :0046625 : sphin this GO lipid binding and also this GO :0046872 : metal ion binding, this GO :0004871 : signal transducer activity, this GO :0005102 : receptor binding, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005174 : CD40 receptor binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0019899 : enzyme binding, this GO :0019903 : protein phosphatase binding, this GO :0031435 : mitogen-activated protein kinase kinase kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, this GO :0032403 : protein complex binding, this GO :0042802 : identical protein binding, this GO :0046625 : sphin this GO lipid binding, this GO :0046872 : metal ion binding, TNF receptor-associated factor 2 |
| Identity: |
12032 |
| Gene: |
TRAF2 |
More about : TRAF2 |
| Long gene name: |
TNF receptor associated factor 2 |
| Synonyms: |
TRAP3 |
| Locus: |
9q34, 3 |
| Discovery year: |
1999-04-28 |
| GenBank acession: |
U12597 |
| Entrez gene record: |
7186 |
| Pubmed identfication: |
7639698 |
| RefSeq identity: |
NM_021138 |
| Classification: |
Ring finger proteins TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000020952 |