| Also known as: |
ICOSLG / ICOSL / ICOS Ligand |
| Other names: |
B7 homolog 2, B7 homolog 2, B7 homologue 2, B7-H2, B7-like protein Gl50, B7-like protein Gl50, B7-related protein 1, B7-related protein 1, B7RP-1, CD_antigen: CD275, ICOS ligand, ICOS ligand, inducible T-cell co-stimulator ligand, transmembrane protein B7-H2 ICOS ligand, ICOS ligand isoform b |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ICOSLG |
| Other gene names: |
B7-H2, B7-H2, B7H2, B7H2, B7RP-1, B7RP-1, B7RP1, B7RP1, CD275, GL50, ICOS-L, ICOSL, ICOSL, ICOSLG, KIAA0653, LICOS, ICOSLG |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b, k |
| Clone: |
2D3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human ICOSL/CD275/B7H2 |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, pH 7, 09% sodium azide, 2, Phosphate-buffered solution |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Store undiluted, Temperature variations in the range between +1C to +7C are tolerable, +Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2D3] (IgG2b, k) ICOSLG / ICOSL / ICOS Ligand |
| Short name: |
Mouse Monoclonal [clone 2D3] (IgG2b, k) ICOSLG / ICOSL / ICOS Ligand Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens inducible T-cellular co-stimulator ligand / ICOSL / inducible T-cell co-stimulator Ligand (Antibody to), Mouse monoclonal [clonality 2D3] (IgG2b, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, ICOSLG and IDBG-5107 and ENSG00000160223 and 102723996, ICOSLG and IDBG-639662 and ENSBTAG00000014880 and 507857, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, Icosl and IDBG-168471 and ENSMUSG00000000732 and 50723, Plasma membranes, inducible T-cell co-stimulator, protein binding, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006972 and hyperosmotic response and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042113 and B cell activation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, 23308, inducible T-cell co-stimulator ligand |
| Identity: |
17087 |
| Gene: |
ICOSLG |
More about : ICOSLG |
| Long gene name: |
inducible T-cell costimulator ligand |
| Synonyms gene: |
ICOSL |
| Synonyms: |
KIAA0653 GL50 B7-H2 B7RP-1 B7H2 B7RP1 ICOS-L CD275 |
| Synonyms name: |
B7-related protein 1 B7 homologue 2 B7 homolog 2 |
| Locus: |
21q22, 3 |
| Discovery year: |
2003-12-12 |
| GenBank acession: |
AB014553 |
| Entrez gene record: |
23308 |
| Pubmed identfication: |
9734811 11007762 |
| RefSeq identity: |
NM_015259 |
| Classification: |
Endogenous ligands C2-set domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000086920 |