| Also known as: |
CXCR4 |
| Other names: |
C-X-C chemokine receptor type 4, C-X-C chemokine receptor type 4, CD184 antigen, CD_antigen: CD184, FB22, Fusin, HM89, LAP-3, LCR1, LESTR, LPS-associated protein 3, LPS-associated protein 3, Leukocyte-derived seven transmembrane domain receptor, Lipopolysaccharide-associated protein 3, NPYRL, SDF-1 receptor, SDF-1 receptor, Stromal cell-derived factor 1 receptor, chemokine (C-X-C motif) receptor 4, fusin, leukocyte-derived seven transmembrane domain receptor, lipopolysaccharide-associated protein 3, neuropeptide Y receptor Y3, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, stromal cell-derived factor 1 receptor, C-X-C chemokine receptor type 4 isoform b |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CXCR4 |
| Other gene names: |
CD184, CXC-R4, CXCR-4, CXCR4, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP-3, LAP3, LCR1, LESTR, LESTR, LPS-associated protein 3, NPY3R, NPYR, NPYRL, NPYY3R, SDF-1 receptor, WHIM, CXCR4 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
12G5 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Chimpanzee, Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Monkey, the reactivity of the antibody may extend to other species which are not listed hereby, Baboon |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, pH 7, 09% sodium azide, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Freezing of the antibody is not recommended, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS), IHC - Frozen), Immunofluorescence (IF), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 12G5] (IgG2a) CXCR4 |
| Short name: |
Mouse Monoclonal [clone 12G5] (IgG2a) CXCR4 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens chemokine (C-X-C motif) receptor 4 (Antibody to), Mouse monoclonal [clonality 12G5] (IgG2a) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD184 and D2S201E and FB22 and HM89 and HSY3RR and LAP-3 and LAP3 and LCR1 and LESTR and NPY3R and NPYR and NPYRL and NPYY3R and WHIM, CXCR4 and IDBG-642187 and ENSBTAG00000001060 and 281736, CXCR4 and IDBG-71032 and ENSG00000121966 and 7852, Cell surfaces, Cxcr4 and IDBG-189999 and ENSMUSG00000045382 and 12767, this GO :0000187 and activation of MAPK activity and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001618 and virus receptor activity and molecular function this GO :0001666 and response to hypoxia and biological process this GO :0001667 and ameboidal cell migration and biological process this GO :0001764 and neuron migration and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0003779 and actin binding and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007281 and germ cell development and biological process this GO :0007420 and brain development and biological process this GO :0008045 and motor neuron axon guidance and biological process this GO :0008354 and germ cell migration and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016032 and viral process and biological process this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0019955 and cytokine binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030260 and entry into host cell and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030426 and growth cone and cellular component this GO :0031252 and cell leading edge and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032027 and myosin light chain binding and molecular function this GO :0042098 and T cell proliferation and biological process this GO :0042119 and neutrophil activation and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043217 and myelin maintenance and biological process this GO :0045087 and innate immune response and biological process this GO :0048699 and generation of neurons and biological process this GO :0048714 and positive regulation of oli this GO dendrocyte differentiation and biological process this GO :0050920 and regulation of chemotaxis and biological process this GO :0061351 and neural precursor cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0003779 : actin binding and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity and also this GO :0016494 : C-X-C chemokine receptor activity and also this GO :0019955 : cytokine binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0032027 : myosin light chain binding and also this GO :0043130 : ubiquitin binding, this GO :0003779 : actin binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0005515 : protein binding, this GO :0015026 : coreceptor activity, this GO :0016494 : C-X-C chemokine receptor activity, this GO :0019955 : cytokine binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0032027 : myosin light chain binding, this GO :0043130 : ubiquitin binding, ubiquitin binding, chemokine (C-X-C motif) receptor 4 |
| Identity: |
2561 |
| Gene: |
CXCR4 |
More about : CXCR4 |
| Long gene name: |
C-X-C motif chemokine receptor 4 |
| Synonyms gene name: |
chemokine (C-X-C motif), receptor 4 (fusin) chemokine (C-X-C motif) receptor 4 |
| Synonyms: |
LESTR NPY3R HM89 NPYY3R D2S201E fusin HSY3RR NPYR CD184 |
| Locus: |
2q22, 1 |
| Discovery year: |
1998-09-17 |
| GenBank acession: |
AF005058 |
| Entrez gene record: |
7852 |
| Pubmed identfication: |
9599023 9379028 |
| Classification: |
CD molecules C-X-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000153583 |
| Locus Specific Databases: |
CXCR4base: Mutation registry for WHIM syndrome (warts, and myelokathexis) LRG_51 , hypogammaglobulinemia, immunodeficiency |