| Also known as: |
STAT1 |
| Other names: |
91kD, 91kDa, Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription-1, transcription factor ISGF-3 components p91/p84, signal transducer and activator of transcription 1-alpha/beta isoform alpha |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
STAT1 |
| Other gene names: |
CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, N/A, STAT1, STAT91, STAT1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
SM1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Bovine, Chicken (at least 90% immunogen sequence identity), Dog, Due to limited knowledge and inability for testing each and every species, Gibbon, Gorilla, Hamster, Horse, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Orangutan, Pig, Rabbit (Oryctolagus cuniculus), Sheep <, the reactivity of the antibody may extend to other species which are not listed hereby, /b>, Bat, Predicted Reactivity: <, Rat (Rattus norvegicus), b> |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, STAT1 peptide sequence 721-733 (DNLLPMSPEEFDE) |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
15 mM sodium azide, Sourced in TCS, approx, pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ SM1] (IgG2b) STAT1 |
| Short name: |
Mouse Monoclonal [clone SM1] (IgG2b) STAT1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
91kDa (Antibody to), sapiens signal transducer and activator on transcription 1, Mouse monoclonal [clonality SM1] (IgG2b) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
91kDa, CANDF7 and IMD31A and IMD31B and IMD31C and ISGF-3 and STAT91, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0007584 and response to nutrient and biological process this GO :0008015 and blood circulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009617 and response to bacterium and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016032 and viral process and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019899 and enzyme binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0031730 and CCR5 chemokine receptor binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0034097 and response to cytokine and biological process this GO :0034240 and negative regulation of macrophage fusion and biological process this GO :0035458 and cellular response to interferon-beta and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051591 and response to cAMP and biological process this GO :0051607 and defense response to virus and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0061326 and renal tubule development and biological process this GO :0072136 and metanephric mesenchymal cell proliferation involved in metanephros development and biological process this GO :0072162 and metanephric mesenchymal cell differentiation and biological process this GO :0072308 and negative regulation of metanephric nephron tubule epithelial cell differentiation and biological process, STAT1 and IDBG-642654 and ENSBTAG00000007867 and 510814, STAT1 and IDBG-77617 and ENSG00000115415 and 6772, Stat1 and IDBG-153162 and ENSMUSG00000026104 and 20846, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000983 and RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and molecular function this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003340 and negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0019899 : enzyme binding and also this GO :0031730 : CCR5 chemokine receptor binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043565 : sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, this GO :0003677 : DNA binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0019899 : enzyme binding, this GO :0031730 : CCR5 chemokine receptor binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0043565 : sequence-specific DNA binding, 515988, signal transducer and activator of transcription 1 |
| Identity: |
11362 |
| Gene: |
STAT1 |
More about : STAT1 |
| Long gene name: |
signal transducer and activator of transcription 1 |
| Synonyms gene name: |
91kD signal transducer and activator of transcription 1, 91kDa , signal transducer and activator of transcription 1 |
| Synonyms: |
STAT91 ISGF-3 |
| Synonyms name: |
transcription factor ISGF-3 components p91/p84 |
| Locus: |
2q32, 2 |
| Discovery year: |
1995-11-08 |
| Entrez gene record: |
6772 |
| Pubmed identfication: |
7885841 |
| RefSeq identity: |
NM_007315 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132699 |
| Locus Specific Databases: |
STAT1base: Mutation registry for STAT1 deficiency LRG_111 |