| Also known as: |
TMBIM6 / Bax Inhibitor 1 |
| Other names: |
Bax inhibitor 1, Testis-enhanced gene transcript protein, Transmembrane BAX inhibitor motif-containing protein 6, bax inhibitor 1, testis enhanced gene transcript, testis-enhanced gene transcript protein, transmembrane BAX inhibitor motif containing 6, transmembrane BAX inhibitor motif-containing protein 6, bax inhibitor 1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TMBIM6 |
| Other gene names: |
BAXI1, BI-1, BI-1, BI1, TEGT, TEGT, TMBIM6, TMBIM6 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
20F430 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Epitope mapping indicates that the antibody recognizes an epitope in the N-terminal region of Bi-1, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, internal and C-terminal regions of human Bax Inhibitor 1, A mixture of three synthetic peptides corresponding to the N-terminal |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 0, 05% sodium azide, 2% gelatin, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 20F430] (IgG2b) TMBIM6 / Bax Inhibitor 1 |
| Short name: |
Mouse Monoclonal [clone 20F430] (IgG2b) TMBIM6 / Bax Inhibitor 1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens transmembrane BCL2-associated X protein inhibitor motif containing 6 / BCL2-associated X protein suppressor 1 (Antibody to), Mouse monoclonal [clonality 20F430] (IgG2b) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BAXI1 and BI-1 and TEGT, TMBIM6 and IDBG-31960 and ENSG00000139644 and 7009, TMBIM6 and IDBG-632492 and ENSBTAG00000018588 and 616210, Tmbim6 and IDBG-183153 and ENSMUSG00000023010 and 110213, nuclei, this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006986 and response to unfolded protein and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032469 and endoplasmic reticulum calcium ion homeostasis and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0070059 and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process, transmembrane BAX inhibitor motif containing 6 |
| Identity: |
11723 |
| Gene: |
TMBIM6 |
More about : TMBIM6 |
| Long gene name: |
transmembrane BAX inhibitor motif containing 6 |
| Synonyms gene: |
TEGT |
| Synonyms gene name: |
testis enhanced gene transcript |
| Synonyms: |
BI-1 BAXI1 |
| Synonyms name: |
BAX inhibitor 1 |
| Locus: |
12q13, 12 |
| Discovery year: |
1994-08-30 |
| GenBank acession: |
X75861 |
| Entrez gene record: |
7009 |
| Pubmed identfication: |
8530040 9660918 |
| RefSeq identity: |
NM_003217 |
| Classification: |
Transmembrane BAX inhibitor motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000169652 |