| Also known as: |
XPC |
| Other names: |
DNA repair protein complementing XP-C cells, DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, complementation group C, mutant xeroderma pigmentosum group C, p125, xeroderma pigmentosum, DNA repair protein complementing XP-C cells |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
XPC |
| Other gene names: |
RAD4, XP3, XPC, XPCC, XPCC, p125, XPC |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
3, 26 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recombinant XPC purified from E Coli |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
26] (IgG1) XPC, Monoclonal [ 3 |
| Short name: |
26] (IgG1) XPC Antibody, Mouse Monoclonal [clone 3 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
complementation group C (Antibody to), sapiens xeroderma pigmentosum, 26] (IgG1) to H, Mouse monoclonal [clonality 3 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA damage recognition and biological process this GO :0000718 and nucleotide-excision repair, DNA damage removal and biological process this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006281 and DNA repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0010224 and response to UV-B and biological process this GO :0031573 and intra-S DNA damage checkpoint and biological process this GO :0042493 and response to drug and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071942 and XPC complex and cellular component this GO :1901990 and regulation of mitotic cell cycle phase transition and biological process, XPC and IDBG-19992 and ENSG00000154767 and 7508, XPC and IDBG-646437 and ENSBTAG00000007362 and 524274, Xpc and IDBG-170258 and ENSMUSG00000030094 and 22591, complementation group C, nuclei, p125 and RAD4 and XP3 and XPCC, protein binding, this GO :0000404 and heteroduplex DNA loop binding and molecular function this GO :0000405 and bubble DNA binding and molecular function this GO :0000715 and nucleotide-excision repair, this GO :0000404 : heteroduplex DNA loop binding, this GO :0000404 : heteroduplex DNA loop binding and also this GO :0000405 : bubble DNA binding and also this GO :0003677 : DNA binding and also this GO :0003684 : damaged DNA binding and also this GO :0003697 : single-stranded DNA binding and also this GO :0005515 : protein binding, this GO :0000405 : bubble DNA binding, this GO :0003677 : DNA binding, this GO :0003684 : damaged DNA binding, this GO :0003697 : single-stranded DNA binding, this GO :0005515 : protein binding, xeroderma pigmentosum |
| Identity: |
12816 |
| Gene: |
XPC |
More about : XPC |
| Long gene name: |
DNA damage recognition and repair factor , XPC complex subunit |
| Synonyms gene name: |
complementation group C , xeroderma pigmentosum |
| Synonyms: |
XPCC RAD4 |
| Synonyms name: |
xeroderma pigmentosum group C protein |
| Locus: |
3p25, 1 |
| Discovery year: |
1992-10-05 |
| Entrez gene record: |
7508 |
| Pubmed identfication: |
1522891 |
| RefSeq identity: |
NM_004628 |
| Classification: |
Xeroderma pigmentosum complementation groups |
| Havana BLAST/BLAT: |
OTTHUMG00000155526 |
| Locus Specific Databases: |
LRG_472 |