| Also known as: |
MRE11A / MRE11 |
| Other names: |
AT-like disease, DNA recombination and repair protein, Double-strand break repair protein MRE11A, MRE11 homolog 1, MRE11 homolog 1, MRE11 homolog A, MRE11 homolog A, MRE11 meiotic recombination 11 homolog A (S, Meiotic recombination 11 homolog 1, Meiotic recombination 11 homolog A, cerevisiae), double-strand break repair protein MRE11A, endo/exonuclease Mre11, meiotic recombination 11 homolog 1, meiotic recombination 11 homolog A, double-strand break repair protein MRE11A isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MRE11A |
| Gene name synonims: |
MRE11 |
| Other gene names: |
ATLD, HNGS1, HNGS1, MRE11, MRE11, MRE11 homolog 1, MRE11 homolog A, MRE11A, MRE11B, MRE11A |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
12D7 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Amino acids 182-582 of Mre11 expressed in E Coli |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
No preservative added, pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 12D7] (IgG1) MRE11A / MRE11 |
| Short name: |
Mouse Monoclonal [clone 12D7] (IgG1) MRE11A / MRE11 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens MRE11A / MRE11 (Antibody to), Mouse monoclonal [clonality 12D7] (IgG1) to H |
| Alternative technique: |
antibodies |
| Identity: |
7230 |
| Gene: |
MRE11 |
More about : MRE11 |
| Long gene name: |
MRE11 homolog, double strand break repair nuclease |
| Synonyms gene: |
MRE11A |
| Synonyms gene name: |
MRE11 meiotic recombination 11 homolog A (S, cerevisiae) MRE11 homolog A, double strand break repair nuclease |
| Synonyms: |
ATLD |
| Synonyms name: |
AT-like disease |
| Locus: |
11q21 |
| Discovery year: |
1995-05-05 |
| GenBank acession: |
BC063458 |
| Entrez gene record: |
4361 |
| Pubmed identfication: |
8530104 24316220 |
| RefSeq identity: |
NM_005591 |
| Classification: |
BRCA1 C complex MRN complex |
| Havana BLAST/BLAT: |
OTTHUMG00000167780 |
| Locus Specific Databases: |
MRE11Abase: Mutation registry for Ataxia-telangiectasia-like disorder (ATLD) LRG_85 |