| Also known as: |
CD266 |
| Other names: |
FGF-inducible 14, FGF-inducible 14, Fibroblast growth factor-inducible immediate-early response protein 14, Tumor necrosis factor receptor superfamily member 12A, Tweak-receptor, fibroblast growth factor-inducible immediate-early response protein 14, member 12A, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 12A, tweak-receptor, type I transmembrane protein Fn14, tumor necrosis factor receptor superfamily member 12A |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD266 |
| Other gene names: |
CD266, FGF-inducible 14, FN14, FN14, TNFRSF12A, TWEAKR, TweakR, TNFRSF12A |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
ITEM-4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The interaction between CD266 and its ligand CD255 (TWEAK), This particular antibody might cross react with speacies outside of the listed ones, a 14kDa type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, and also with Rat-1 cells in flow cytometry, and at elevated levels by human brain and liver tumours, and studies have shown that CD255-induced apoptosis of some tumour cell lines is mediated by CD266 Clone ITEM-4 is cross-reactive with mouse CD266, including the heart, induces the proliferation and migration of endothelial cells and also angiogenesis, lung and kidney, otherwise known as Fn14/TWEAK Receptor, CD266 This item recognises human CD266 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD266 |
| Short name: |
MOUSE Anti-HUMAN CD266 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD266 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
18152 |
| Gene: |
TNFRSF12A |
More about : TNFRSF12A |
| Long gene name: |
TNF receptor superfamily member 12A |
| Synonyms gene name: |
member 12A , tumor necrosis factor receptor superfamily |
| Synonyms: |
FN14 TweakR CD266 |
| Locus: |
16p13, 3 |
| Discovery year: |
2002-12-20 |
| GenBank acession: |
AB035480 |
| Pubmed identfication: |
10751351 10551889 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000129001 |