| Also known as: |
JAM-C |
| Other names: |
JAM-2, Junctional adhesion molecule 3, Junctional adhesion molecule C, junction adhesion molecule 3, junction cell adhesion molecule 3, junction cell adhesion molecule C, junctional adhesion molecule 3, junctional adhesion molecule C, junctional adhesion molecule C |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
JAM-C |
| Other gene names: |
1110002N23Rik, JAM-3, JAM-3, JAM-C, JAM-C, Jam3, Jcam3, Jam3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
CRAM-18 F26 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Clone CRAM-18 F26 has been reported to inhibit transendothelial migration, It plays a role in tight junctions and inflammatory processes and interacts with JAM-A and JAM-B, JAM-C is expressed at junctions between endothelial and epithelial cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, also known as JAM-3 and, amongst other cell types, as JAM-2, as well as on leukocytes, historically, platelets, vascular smooth muscle cells and fibroblasts, JAM-C Clone CRAM-18 F26 recognises mouse and human Junctional adhesion molecule C (JAM-C) |
| Form/Appearance: |
Biotin (Purified IgG conjugated to Biotin - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunofluorescence (IF) |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Biotinylated |
| Gene target: |
JAM-C: |
| Short name: |
RAT ANTI MOUSE JAM-C: Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
RAT antibody to MOUSE JAM-C:biotinilated (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15532 |
| Gene: |
JAM3 |
More about : JAM3 |
| Long gene name: |
junctional adhesion molecule 3 |
| Synonyms: |
JAM-C JAMC |
| Locus: |
11q25 |
| Discovery year: |
2001-04-26 |
| GenBank acession: |
AF356518 |
| Entrez gene record: |
83700 |
| RefSeq identity: |
NM_032801 |
| Classification: |
V-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167130 |