| Also known as: |
LIPOPROTEIN LIPASE |
| Other names: |
Lipoprotein lipase, N/A, lipoprotein lipase, lipoprotein lipase<, lipoprotein lipase |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
LPL, LPL, N/A, LPL |
| Gene name synonims: |
LPL, LPL, N/A, LPL |
| Other gene names: |
LPL, LPL, N/A, LPL |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
5D2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Bovine |
| Specificity and cross-reactivity: |
Clone 5D2 has been shown to inhibit the activity of human LPL<, LPL receptor, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_A deficiency of LPL can result in hypertriglyceridemia, _x000D__x000D_Clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, a member of the AB hydrolase superfamily, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and binds to LPL sequences involved in LPL, and heparin interactions, and in particular the relationship between LPL and apolipoprotein E (ApoE), and is widely used in human studies, and many studies have focused on the critical role which LPL plays in the pathogenesis of atherosclerosis, and the release of free fatty acids into peripheral tissues, both of which are secreted in significant amounts by macrophages in developing arterial wall lesions, which plays a pivotal role in lipoprotein metabolism and transport, (2, /sup>, 3)<, LIPOPROTEIN LIPASE This item specifically recognises an epitope within amino acids 380-410 of lipoprotein lipase (LPL), sup> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
LIPOPROTEIN LIPASE |
| Short name: |
MOUSE Anti-LIPOPROTEIN LIPASE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-LIPOPROTEIN LIPASE (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6620 |
| Gene: |
LIPD |
More about : LIPD |
| Long gene name: |
lipoprotein lipase |
| Synonyms: |
LPL |
| Locus: |
8p21, 3 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
4023 |
| Pubmed identfication: |
3823907 3597382 3692485 |
| Classification: |
Lipases |
| Havana BLAST/BLAT: |
OTTHUMG00000036645 |