| Also known as: |
ABCA1 |
| Other names: |
ATP-binding cassette, ATP-binding cassette 1, ATP-binding cassette sub-family A member 1, ATP-binding cassette sub-family A member 1, ATP-binding cassette transporter 1, ATP-binding cassette transporter 1, member 1, sub-family A (ABC1), ATP-binding cassette sub-family A member 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ABCA1 |
| Other gene names: |
ABC-1, ABC-1, Abc1, Abc1, Abca1, Abca1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
5A1-1422 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
ABCA1 is a member of the ABC-A sub-family, ABCA1 may play an important role in protecting against cardiovascular disease, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes, The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency, which acts as a lipid translocator, ABCA1 This item recognises murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ABCA1 |
| Short name: |
RAT ANTI MOUSE ABCA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 1 (Antibody to), sub-family A (ABC1), RAT antibody to MOUSE adenosine triphosphate-binding cassette |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ABC-1 and ABC1 and CERP and HDLDT1 and TGD, ABCA1 and IDBG-79441 and ENSG00000165029 and 19, ATPase binding, Abca1 and IDBG-147642 and ENSMUSG00000015243 and 11303, BT, Cell surfaces, engulfment and biological process this GO :0007040 and lysosome organization and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008509 and anion transmembrane transporter activity and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010887 and negative regulation of cholesterol storage and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0015914 and phospholipid transport and biological process this GO :0016197 and endosomal transport and biological process this GO :0016887 and ATPase activity and molecular function this GO :0017127 and cholesterol transporter activity and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0030139 and endocytic vesicle and cellular component this GO :0030301 and cholesterol transport and biological process this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0031267 and small GTPase binding and molecular function this GO :0032367 and intracellular cholesterol transport and biological process this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0034186 and apolipoprotein A-I binding and molecular function this GO :0034188 and apolipoprotein A-I receptor activity and molecular function this GO :0034364 and high-density lipoprotein particle and cellular component this GO :0034380 and high-density lipoprotein particle assembly and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0038027 and apolipoprotein A-I-mediated signaling pathway and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042158 and lipoprotein biosynthetic process and biological process this GO :0042493 and response to drug and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043691 and reverse cholesterol transport and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045332 and phospholipid translocation and biological process this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050702 and interleukin-1 beta secretion and biological process this GO :0051117 and ATPase binding and molecular function this GO :0055091 and phospholipid homeostasis and biological process this GO :0055098 and response to low-density lipoprotein particle stimulus and biological process this GO :0060155 and platelet dense granule organization and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071397 and cellular response to cholesterol and biological process, member 1, sub-family A (ABC1), this GO :0002790 and peptide secretion and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005548 and phospholipid transporter activity and molecular function this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006497 and protein lipidation and biological process this GO :0006911 and pha this GO cytosis, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005543 : phospholipid binding and also this GO :0005548 : phospholipid transporter activity and also this GO :0008509 : anion transmembrane transporter activity and also this GO :0015485 : cholesterol binding and also this GO :0016887 : ATPase activity and also this GO :0017127 : cholesterol transporter activity and also this GO :0019905 : syntaxin binding and also this GO :0031267 : small GTPase binding and also this GO :0034185 : apolipoprotein binding and also this GO :0034186 : apolipoprotein A-I binding and also this GO :0034188 : apolipoprotein A-I receptor activity and also this GO :0051117 : ATPase binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005543 : phospholipid binding, this GO :0005548 : phospholipid transporter activity, this GO :0008509 : anion transmembrane transporter activity, this GO :0015485 : cholesterol binding, this GO :0016887 : ATPase activity, this GO :0017127 : cholesterol transporter activity, this GO :0019905 : syntaxin binding, this GO :0031267 : small GTPase binding, this GO :0034185 : apolipoprotein binding, this GO :0034186 : apolipoprotein A-I binding, this GO :0034188 : apolipoprotein A-I receptor activity, this GO :0051117 : ATPase binding, 89249 and IDBG-637291 and ENSBTAG00000020661 and 535379, ATP-binding cassette |
| Identity: |
29 |
| Gene: |
ABCA1 |
More about : ABCA1 |
| Long gene name: |
ATP binding cassette subfamily A member 1 |
| Synonyms gene: |
ABC1 HDLDT1 |
| Synonyms gene name: |
ATP-binding cassette, member 1 , sub-family A (ABC1) |
| Synonyms: |
TGD |
| Synonyms name: |
Tangier disease |
| Locus: |
9q31, 1 |
| Discovery year: |
2005-03-17 |
| GenBank acession: |
AJ012376 |
| Entrez gene record: |
19 |
| Pubmed identfication: |
8088782 10431236 10431237 10431238 |
| RefSeq identity: |
NM_005502 |
| Classification: |
ATP binding cassette subfamily A |
| Havana BLAST/BLAT: |
OTTHUMG00000020417 |