| Also known as: |
CD103 |
| Other names: |
Integrin alpha M290, Integrin alpha-E, epithelial-associated, integrin alpha E, integrin alpha M290, integrin alpha-E, integrin alpha-E isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD103 |
| Other gene names: |
A530055J10, CD103, Itgae, N/A, aM290, alpha-E1, alpha-M290, Itgae |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
20000000 |
| Host organism: |
Hamster |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule ?E?7, CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells, Clone 2E7 has been reported to also recognise the ?E?7 complex, It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ?E?7 complex is a receptor for E-cadherin, The beta 7 subunit can also interact with other integrin alpha chains, This complex is sometimes referred to as CD103, This particular antibody might cross react with speacies outside of the listed ones, otherwise known as Integrin alpha-E, though strictly speaking CD103 only refers to the alpha chain, CD103 This item recognises mouse CD103 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistology - Frozen (IHC), Immunoprecipitation (IP) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD103 |
| Short name: |
HAMSTER ANTI MOUSE CD103 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HAMSTER antibody to MOUSE CD103 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6147 |
| Gene: |
ITGAE |
More about : ITGAE |
| Long gene name: |
integrin subunit alpha E |
| Synonyms gene name: |
alpha E (antigen CD103, alpha polypeptide) , human mucosal lymphocyte antigen 1, integrin |
| Synonyms: |
CD103 HUMINAE |
| Synonyms name: |
alpha polypeptide , antigen CD103 human mucosal lymphocyte antigen 1 |
| Locus: |
17p13, 2 |
| Discovery year: |
1997-06-09 |
| GenBank acession: |
L25851 |
| Entrez gene record: |
3682 |
| Pubmed identfication: |
8119947 |
| RefSeq identity: |
NM_002208 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000177634 |