| Also known as: |
BIM |
| Other names: |
BCL2-like 11 (apoptosis facilitator), Bcl-2-like protein 11, Bcl2 interacting mediator of cell death, Bcl2-interacting mediator of cell death, bcl-2-like protein 11, bcl2-L-11, bcl2-interacting mediator of cell death, bcl-2-like protein 11 isoform 3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
BIM |
| Other gene names: |
1500006F24Rik, Bcl2-L-11, Bcl2l11, Bim, Bim, Bod, Bcl2l11 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
151-149 |
| Host organism: |
Hamster |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Bcl-XL and Bcl-w, Bim is a pro-apoptotic protein within the Bcl-2 family, Bim is known to interact with pro-survival proteins including Bcl-2, Bim is released from microtubules and mediates caspase-dependent apoptosis, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Upon certain apoptotic stimuli, also known as Bod, where it is maintained in an inactive conformation by phosphorylation or through binding to the microtubule-associated dynein motor complex, which functions within the intrinsic apoptosis pathway, BIM This item is specific for human Bcl-2 interacting mediator of cell death (Bim), _x000D_, _x000D__x000D_It is expressed in a variety of cell types |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
BIM |
| Short name: |
HAMSTER ANTI MOUSE BIM Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HAMSTER antibody to MOUSE BIM (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
994 |
| Gene: |
BCL2L11 |
More about : BCL2L11 |
| Long gene name: |
BCL2 like 11 |
| Synonyms gene name: |
BCL2-like 11 (apoptosis facilitator) |
| Synonyms: |
BOD BimL BimEL BimS BIM |
| Locus: |
2q13 |
| Discovery year: |
1999-12-10 |
| GenBank acession: |
AF032458 |
| Entrez gene record: |
10018 |
| Pubmed identfication: |
9731710 9430630 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000131256 |
| Locus Specific Databases: |
LRG_620 |