| Also known as: |
AMPK ALPHA 1/2 |
| Other names: |
5'-AMP-activated protein kinase, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, ACACA kinase, ACACA kinase, AMP -activate kinase alpha 1 subunit, AMP-activated, AMP-activated protein kinase, AMPK alpha 1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase (EC:2, HMGCR kinase, HMGCR kinase, Hydroxymethylglutaryl-CoA reductase kinase (EC:2, Tau-protein kinase PRKAA1 (EC:2, acetyl-CoA carboxylase kinase, alpha 1 catalytic subunit, alpha-1, catalytic, catalytic alpha-1 chain, hydroxymethylglutaryl-CoA reductase kinase, protein kinase, tau-protein kinase PRKAA1, 11, 11, 11, 26), 27), 31), 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1, 7, 7, 7 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
AMPK ALPHA 1/2 |
| Other gene names: |
ACACA kinase, AMPK, AMPK subunit alpha-1, AMPK1, AMPKa1, HMGCR kinase, PRKAA1, PRKAA1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
1, 84 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Drosophila |
| Specificity and cross-reactivity: |
AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes, AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, This particular antibody might cross react with speacies outside of the listed ones, _x000D_AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes, exercise, ischemia, low glucose levels, which is stabilised by non-catalytic regulatory beta- and gamma- subunits, AMPK ALPHA 1/2 This item recognises both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology - Frozen (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
AMPK ALPHA 1/2 |
| Short name: |
MOUSE Anti-AMPK ALPHA 1/2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-AMPK a 1/2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9377 |
| Gene: |
PRKAA2 |
More about : PRKAA2 |
| Long gene name: |
protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene: |
PRKAA |
| Synonyms gene name: |
AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Synonyms: |
AMPK AMPKa2 |
| Locus: |
1p32, 2 |
| Discovery year: |
1995-12-12 |
| GenBank acession: |
BC069823 |
| Entrez gene record: |
5563 |
| Pubmed identfication: |
7959015 |
| RefSeq identity: |
NM_006252 |
| Havana BLAST/BLAT: |
OTTHUMG00000008282 |