| Also known as: |
TROPOMODULIN 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
TRM-17 (Mab17) |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Chicken |
| Specificity and cross-reactivity: |
, Clone TRM-17 functionally inhibits the binding of Tmod1 to tropomyosin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The binding of the N-terminal region of Tmod1 with the actin-binding protein tropomyosin blocks the elongation and depolymerization of actin filaments, This particular antibody might cross react with speacies outside of the listed ones, Tmod1 is a sarcomeric protein highly expressed by erythrocytes, contributing to the geometry of the membrane skeleton, heart and skeletal muscle, otherwise known as erythrocyte tropomodulin (E-Tmod), which binds to and caps pointed ends of actin filaments to prevent thin filament elongation, TROPOMODULIN 1 This item specifically recognises an epitope between amino acid residues 6-57 within the N-terminal (NT) region of Tropomodulin 1 (Tmod1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Functional Assay (FA), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
TROPOMODULIN 1 |
| Short name: |
MOUSE Anti-TROPOMODULIN 1 (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-TROPOMODULIN 1 (N-TERMINAL) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11871 |
| Gene: |
TMOD1 |
More about : TMOD1 |
| Long gene name: |
tropomodulin 1 |
| Synonyms gene: |
D9S57E TMOD |
| Synonyms: |
ETMOD |
| Locus: |
9q22, 33 |
| Discovery year: |
1991-05-21 |
| Entrez gene record: |
7111 |
| Pubmed identfication: |
1370827 8661028 |
| RefSeq identity: |
NM_003275 |
| Classification: |
Tropomodulins |
| Havana BLAST/BLAT: |
OTTHUMG00000020325 |