| Also known as: |
ACTH |
| Other names: |
ACTHMelanotropin alpha, Adrenocorticotropic hormone, Alpha-MSHCorticotropin-like intermediary peptide, Alternative name(s):, Alternative name(s):, Alternative name(s):, Alternative name(s):, Alternative name(s):, Alternative name(s):, Beta-LPHLipotropin gamma, Beta-MSH, CLIPLipotropin beta, Corticotropin-lipotropinCleaved into the following 11 chains:NPPMelanotropin gamma, Gamma-LPHMelanotropin beta, Gamma-MSHPotential peptideCorticotropin, Pro-opiomelanocortin, adrenocorticotropic hormone, adrenocorticotropin, alpha-MSH, alpha-melanocyte-stimulating hormone, beta-LPH, beta-MSH, beta-endorphin, beta-melanocyte-stimulating hormone, corticotropin-like intermediary peptide, corticotropin-lipotropin, gamma-LPH, gamma-MSH, lipotropin beta, lipotropin gamma, melanotropin alpha, melanotropin beta, melanotropin gamma, met-enkephalin, opiomelanocortin prepropeptide, pro-ACTH-endorphin, pro-opiomelanocortin, proopiomelanocortin, proopiomelanocortin preproprotein, pro-opiomelanocortin preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ACTH |
| Other gene names: |
ACTH, ACTH, CLIP, CLIP, LPH, MSH, NPP, POC, POMC, POMC, POMC |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
57 (BGN/1388/66) |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies have shown that the administration of 1-24 ACTH increases blood pressure, This item cross-reacts with rat N-terminal ACTH, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_ACTH, _x000D__x000D_This item does not recognise 17-39 ACTH (CLIP), acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, as a synthetic analogue of naturally-occurring Adrenocorticotropic Hormone, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation, in association with increased cardiac output, involved in the response to stress, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, ACTH This item recognises 1-24 ACTH (Synacthen) which, _x000D_ |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, only, the antibody should be stored undiluted, Store the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
Immunohistology - Paraffin (IHC), ELISA (EIA) |
| Description: |
or corticotrophins, Adrenocorticotropic hormone (ACTH) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ACTH |
| Short name: |
MOUSE Anti-HUMAN ACTH Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens ACTH (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
9201 |
| Gene: |
POMC |
More about : POMC |
| Long gene name: |
proopiomelanocortin |
| Synonyms: |
MSH POC CLIP ACTH NPP LPH |
| Synonyms name: |
adrenocorticotropin beta-lipotropin alpha-melanocyte stimulating hormone beta-melanocyte stimulating hormone beta-endorphin adrenocorticotropic hormone opiomelanocortin prepropeptide |
| Locus: |
2p23, 3 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
5443 |
| Pubmed identfication: |
6254047 9620771 |
| RefSeq identity: |
NM_001035256 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000094764 |