| Also known as: |
TWEAK |
| Other names: |
TNF-related weak inducer of apoptosis, TNF-related weak inducer of apoptosis, Tumor necrosis factor ligand superfamily member 12, member 12, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 12, tumor necrosis factor ligand superfamily member 12 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TWEAK |
| Other gene names: |
Apo3l, Dr3l, Dr3lg, TWEAK, Tnfsf12, Tweak, Tnfsf12 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
MTW-1 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Clone MTW-1 has been reported to block ligand binding <, It is involved in the induction of inflammatory cytokines, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TWEAK binds to the TWEAK receptor FN14 (TWEAK-R) to weakly induce apoptosis in some cell types, TWEAK is expressed on a broad range of adult and foetal tissues, This cytokine also promotes proliferation and migration of endothelial cells and acts as a regulator of angiogenesis, This particular antibody might cross react with speacies outside of the listed ones, /i>, TWEAK This item recognises mouse TWEAK (TNF-like weak inducer of apoptosis) a type II transmembrane TNF superfamily member, i>, in vitro< |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
TWEAK |
| Short name: |
RAT ANTI MOUSE TWEAK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE TWEAK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11927 |
| Gene: |
TNFSF12 |
More about : TNFSF12 |
| Long gene name: |
tumor necrosis factor superfamily member 12 |
| Synonyms gene name: |
member 12 , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
TWEAK DR3LG APO3L |
| Locus: |
17p13, 1 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF030099 |
| Entrez gene record: |
8742 |
| Pubmed identfication: |
9405449 9560343 |
| RefSeq identity: |
NM_003809 |
| Classification: |
Tumor necrosis factor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000108148 |