| Also known as: |
CD243 |
| Other names: |
ATP-binding cassette, ATP-binding cassette sub-family B member 1, Multidrug resistance protein 1, P-glycoprotein 1, P-glycoprotein 1, colchicin sensitivity, doxorubicin resistance, member 1, multidrug resistance protein 1, sub-family B (MDR/TAP), multidrug resistance protein 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD243 |
| Other gene names: |
ABC20, ABCB1, CD243, CLCS, GP170, MDR1, MDR1, P-GP, PGY1, PGY1, ABCB1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
JSB-1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD243, In malignant conditions increased expression of P-glycoprotein may be associated with multi-drug resistance, In normal tissues P-glycoprotein is expressed in liver, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This clone has also been reported to be suitable for Western blot analysis, This particular antibody might cross react with speacies outside of the listed ones, a plasma membrane associated molecule which is important in mediating resistance to cytotoxic drugs, adrenal gland and lung, and the detection of this can have important consequences for treatment, colon, kidney, CD243 This item recognises the 170-180kD P-glycoprotein |
| Form/Appearance: |
Concentrate (Concentrated Tissue Culture Supernatant - liquid) |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD243 |
| Short name: |
MOUSE Anti-HUMAN CD243 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD243 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
40 |
| Gene: |
ABCB1 |
More about : ABCB1 |
| Long gene name: |
ATP binding cassette subfamily B member 1 |
| Synonyms gene: |
PGY1 MDR1 CLCS |
| Synonyms gene name: |
colchicin sensitivity ATP-binding cassette, member 1 , sub-family B (MDR/TAP) |
| Synonyms: |
P-gp CD243 GP170 ABC20 |
| Synonyms name: |
multidrug resistance protein 1 |
| Locus: |
7q21, 12 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M14758 |
| Entrez gene record: |
5243 |
| Pubmed identfication: |
3027054 |
| RefSeq identity: |
NM_000927 |
| Classification: |
CD molecules ATP binding cassette subfamily B |
| Havana BLAST/BLAT: |
OTTHUMG00000023393 |