| Also known as: |
CD73 |
| Other names: |
5'-NT, 5'-nucleotidase, 5'-nucleotidase, 5'-nucleotidase, Ecto-5'-nucleotidase, Purine 5-Prime-Nucleotidase, ecto (CD73), ecto-5'-nucleotidase, 5'-nucleotidase isoform 2 preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD73 |
| Other gene names: |
5'-NT, CD73, E5NT, NT, NT5, NT5, NT5E, NTE, NTE, eN, eNT, NT5E |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
2B6 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
A decrease in CD73 activity has been associated with several immunodeficiency disorders including AIDS and Wiskott-Aldrich syndrome, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD73 is expressed by subpopulations of T and B lymphocytes, a GPI-anchored enzyme and member of the 5'-nucleotidase family, acting as a lymphocyte maturation marker, and CD73 is expressed on a variety of lymphomas and leukaemias, and can also mediate co-stimulatory signals in T cell activation, and increases during lymphocyte development, including CLL and ALL, otherwise known as ecto-5'-nucleotidase, which catalyzes the dephosphorylation of 5'-mononucleotides into their corresponding nucleosides, CD73 This item specifically recognises human CD73 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD73 |
| Short name: |
MOUSE Anti-HUMAN CD73 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD73 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
8021 |
| Gene: |
NT5E |
More about : NT5E |
| Long gene name: |
5', -nucleotidase ecto |
| Synonyms gene: |
NT5 |
| Synonyms gene name: |
5', ecto (CD73) , nucleotidase (CD73) 5', -nucleotidase |
| Synonyms: |
CD73 eN eNT CALJA |
| Locus: |
6q14, 3 |
| Discovery year: |
1989-02-23 |
| GenBank acession: |
X55740 |
| Entrez gene record: |
4907 |
| Classification: |
5', -nucleotidases CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000015139 |