| Also known as: |
CD257 |
| Other names: |
ApoL related ligand TALL-1, B lymphocyte stimulator, B-cell-activating factor, B-cell-activating factor, B-lymphocyte stimulator, BAFF, BLyS, Delta4 BAFF, Dendritic cell-derived TNF-like molecule, TNF and ApoL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNF- and APOL-related leukocyte expressed ligand 1, Tumor necrosis factor ligand superfamily member 13B, delta BAFF, dendritic cell-derived TNF-like molecule, member 13b, member 20, tumor necrosis factor (ligand) superfamily, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 13B, tumor necrosis factor-like protein ZTNF4, tumor necrosis factor ligand superfamily member 13B isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD257 |
| Other gene names: |
BAFF, BAFF, BLYS, BLYS, BLyS, CD257, DTL, TALL-1, TALL-1, TALL1, TALL1, THANK, TNFSF13B, TNFSF20, TNFSF20, ZTNF4, ZTNF4, TNFSF13B |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
T7-241 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD269 (BCMA) and CD268 (BAFFR) receptors, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, T cells and dendritic cells and acts through binding to CD267 (TACI), This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD257 is expressed by monocytes, a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, differentiation and proliferation of B cells, macrophages, survival, the latter interaction playing a critical role in the activation, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus, CD257 This item specifically recognises CD257 (otherwise known as BAFF/BLyS) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of reconstitution, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD257 |
| Short name: |
MOUSE Anti-HUMAN CD257 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD257 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11929 |
| Gene: |
TNFSF13B |
More about : TNFSF13B |
| Long gene name: |
tumor necrosis factor superfamily member 13b |
| Synonyms gene: |
TNFSF20 |
| Synonyms gene name: |
member 13b , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
BAFF THANK BLYS TALL-1 TALL1 CD257 |
| Locus: |
13q33, 3 |
| Discovery year: |
1999-07-19 |
| GenBank acession: |
AF136293 |
| Entrez gene record: |
10673 |
| Pubmed identfication: |
10331498 10359578 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000017329 |