| Also known as: |
CD36 |
| Other names: |
CD36 antigen, GPIIIB, GPIIIB, Glycoprotein IIIb, PAS IV, PAS IV, PAS-4, PAS-4, Platelet glycoprotein 4, Platelet glycoprotein IV, fatty acid translocase, glycoprotein IIIb, platelet glycoprotein 4, platelet glycoprotein IV, platelet glycoprotein 4 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD36 |
| Other gene names: |
Cd36, FAT, GPIIIB, GPIV, GPIV, Scarb3, Cd36 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
MF3 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Antibodies produced by clone MF3 have been shown to inhibit IL-4 induced thioglycollate-elicited peritoneal macrophage fusion and significantly block IL-4/GM-CSF-induced bone-marrorw derived macrophage fusion, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with <, The CD36 molecule is type B scavenger receptor, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD36 has diverse functions and is reported to play a role in innate immunity, an 85kD transmembrane glycoprotein which is primarily expressed on platelets, and may be involved in the development of atherosclerotic lesions and the formation of foam cells, anionic phospholipids, monocytes/macrophages, oxidized low density lipoproteins and long chain fatty acids, platelet adhesion/aggregation and long chain fatty acid transport, smooth muscle and endothelial cells, which binds to multiple ligands including thrombospondin, /i>, CD36 This item recognises mouse CD36, Plasmodium falciparum<, i> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD36 |
| Short name: |
RAT ANTI MOUSE CD36 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD36 molecule (thrombospondin receptor) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BDPLT10 and CHDS7 and FAT and GP3B and GP4 and GPIV and PASIV and SCARB3, CD36 and IDBG-24023 and ENSG00000135218 and 948, Cd36 and IDBG-136838 and ENSMUSG00000002944 and 12491, Extracellular, TAP-dependent and biological process this GO :0002576 and platelet degranulation and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0005041 and low-density lipoprotein receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006910 and pha this GO cytosis, engulfment and biological process this GO :0060907 and positive regulation of macrophage cytokine production and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070892 and lipoteichoic acid receptor activity and molecular function this GO :0071221 and cellular response to bacterial lipopeptide and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0071447 and cellular response to hydroperoxide and biological process this GO :0071813 and lipoprotein particle binding and molecular function this GO :2000121 and regulation of removal of superoxide radicals and biological process this GO :2000334 and positive regulation of blood microparticle formation and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, lipoprotein particle binding, recognition and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008035 and high-density lipoprotein particle binding and molecular function this GO :0008289 and lipid binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010886 and positive regulation of cholesterol storage and biological process this GO :0015911 and plasma membrane long-chain fatty acid transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019915 and lipid storage and biological process this GO :0019934 and cGMP-mediated signaling and biological process this GO :0030168 and platelet activation and biological process this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030194 and positive regulation of blood coagulation and biological process this GO :0030301 and cholesterol transport and biological process this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0031092 and platelet alpha granule membrane and cellular component this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034381 and plasma lipoprotein particle clearance and biological process this GO :0034383 and low-density lipoprotein particle clearance and biological process this GO :0035634 and response to stilbenoid and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0042992 and negative regulation of transcription factor import into nucleus and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043277 and apoptotic cell clearance and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044539 and long-chain fatty acid import and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0055096 and low-density lipoprotein particle mediated signaling and biological process this GO :0060100 and positive regulation of pha this GO cytosis, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002221 and pattern recognition receptor signaling pathway and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005041 : low-density lipoprotein receptor activity, this GO :0005041 : low-density lipoprotein receptor activity and also this GO :0005515 : protein binding and also this GO :0008035 : high-density lipoprotein particle binding and also this GO :0008289 : lipid binding and also this GO :0030169 : low-density lipoprotein particle binding and also this GO :0050431 : transforming growth factor beta binding and also this GO :0070053 : thrombospondin receptor activity and also this GO :0070892 : lipoteichoic acid receptor activity and also this GO :0071813 : lipoprotein particle binding, this GO :0005515 : protein binding, this GO :0008035 : high-density lipoprotein particle binding, this GO :0008289 : lipid binding, this GO :0030169 : low-density lipoprotein particle binding, this GO :0050431 : transforming growth factor beta binding, this GO :0070053 : thrombospondin receptor activity, this GO :0070892 : lipoteichoic acid receptor activity, this GO :0071813 : lipoprotein particle binding, CD36 molecule (thrombospondin receptor) |
| Identity: |
1663 |
| Gene: |
CD36 |
More about : CD36 |
| Long gene name: |
CD36 molecule |
| Synonyms gene name: |
CD36 antigen (collagen type I receptor, thrombospondin receptor) CD36 molecule (thrombospondin receptor) |
| Synonyms: |
SCARB3 GPIV FAT GP4 GP3B |
| Locus: |
7q21, 11 |
| Discovery year: |
1993-06-04 |
| GenBank acession: |
Z32770 |
| Entrez gene record: |
948 |
| Pubmed identfication: |
7503937 |
| RefSeq identity: |
NM_001001547 |
| Classification: |
CD molecules Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000155383 |