| Also known as: |
CD83 |
| Other names: |
CD83 antigen, CD83 antigen, CD83 antigen, N/A, mCD83, CD83 antigen |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD83 |
| Other gene names: |
Cd83, N/A, mCD83, Cd83 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
3D11 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Activated dendritic cells and B-cells release a soluble form of CD83 that is reported to have an immunosuppressive effect, B-cell function and peripheral T-cell activation, CD83 plays a role in the regulation of antigen presentation, Originally described as a maturation marker for dendritic cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 45kD type 1 glyoprotein belonging to the immunoglobulin superfamily, suggesting a therapeutic role for sCD83 in the regulation of immune disorders, thymic T-cell maturation, CD83 This item recognises murine CD83 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from the date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD83 |
| Short name: |
RAT ANTI MOUSE CD83 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD83 molecule (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BL11 and HB15, CD83 and IDBG-62750 and ENSG00000112149 and 9308, CD83 and IDBG-636028 and ENSBTAG00000031430 and 617034, Cd83 and IDBG-147707 and ENSMUSG00000015396 and 12522, Cell surfaces, alpha-beta T cell differentiation and biological process, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006959 and humoral immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0014070 and response to organic cyclic compound and biological process this GO :0032713 and negative regulation of interleukin-4 production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032743 and positive regulation of interleukin-2 production and biological process this GO :0043372 and positive regulation of CD4-positive, this GO :0005515 : protein binding, this GO :0005515 : protein binding, CD83 molecule |
| Identity: |
1703 |
| Gene: |
CD83 |
More about : CD83 |
| Long gene name: |
CD83 molecule |
| Synonyms gene name: |
CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) CD83 molecule |
| Synonyms: |
HB15 BL11 |
| Locus: |
6p23 |
| Discovery year: |
1999-03-26 |
| GenBank acession: |
Z11697 |
| Entrez gene record: |
9308 |
| Pubmed identfication: |
1378080 8422464 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000014283 |