| Also known as: |
CD98 |
| Other names: |
4F2 cell-surface antigen heavy chain, 4F2 cell-surface antigen heavy chain, CD98 antigen, CD98 heavy chain, N/A, antigen identified by monoclonal antibodies 4F2, member 2, solute carrier family 3 (activators of dibasic and neutral amino acid transport), type II transmembrane protein, 4F2 cell-surface antigen heavy chain isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD98 |
| Other gene names: |
4F2, 4F2HC, 4F2hc, AI314110, Cd98, Ly-10, Ly-m10, Ly10, Mdu1, Mdu1, Mgp-2hc, NACAE, Slc3a2, Slc3a2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
1, 4, 4, H202-529 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells, a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complex, and therefore may play an important role in tumorigenesis, CD98 This item recognises murine CD98 (also known as 4F2 and SLC3A2) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD98 |
| Short name: |
RAT ANTI MOUSE CD98 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD98 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11063 |
| Gene: |
SLC7A5 |
More about : SLC7A5 |
| Long gene name: |
solute carrier family 7 member 5 |
| Synonyms gene name: |
L system), member 5 , solute carrier family 7 (amino acid transporter light chain |
| Synonyms: |
LAT1 E16 D16S469E MPE16 CD98 |
| Locus: |
16q24, 2 |
| Discovery year: |
1999-01-28 |
| GenBank acession: |
AF077866 |
| Entrez gene record: |
8140 |
| Pubmed identfication: |
9751058 7829099 |
| RefSeq identity: |
NM_003486 |
| Classification: |
Solute carriers CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000137658 |