| Also known as: |
CD50 |
| Other names: |
CDw50, ICAM-3, ICAM-R, Intercellular adhesion molecule 3, intercellular adhesion molecule 3, intercellular adhesion molecule 3, intercellular adhesion molecule-3, intercellular adhesion molecule 3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD50 |
| Other gene names: |
CD50, CDW50, ICAM-3, ICAM-R, ICAM3, ICAM3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
Bu65 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD50 is an 110kD type I transmembrane glycoprotein which is expressed mainly on resting leukocytes, It has also been implicated in limiting HIV-1 replication, It interacts with lymphocyte function-associated antigen-1 (LFA-1) and DC-SIGN, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD50 expression induces cancer cell proliferation and over-expression may contribute to cancer progression, also known as Inter-cellular adhesion molecule-3 (ICAM-3), and is involved in the intercellular adhesion of leukocytes and augments CD3 signalling in T-lymphocyte activation, CD50 This item recognises human CD50 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD50 |
| Short name: |
MOUSE Anti-HUMAN CD50 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD50 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
5346 |
| Gene: |
ICAM3 |
More about : ICAM3 |
| Long gene name: |
intercellular adhesion molecule 3 |
| Synonyms: |
CDW50 ICAM-R CD50 |
| Locus: |
19p13, 2 |
| Discovery year: |
1994-05-19 |
| Entrez gene record: |
3385 |
| Pubmed identfication: |
1448174 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180410 |