| Also known as: |
LEPTIN |
| Other names: |
Leptin, Obese protein, Obesity factor, homolog of, leptin, leptin, leptin (murine obesity homolog), leptin (obesity homolog, mouse, mouse), obese, obese protein, obesity factor, leptin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
LEPTIN |
| Other gene names: |
LEP, LEPD, OB, OB, OBS, OBS, LEP |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
9C10 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
However, It is produced by fat cells and the placenta, Lack of functional leptin and leptin receptors lead to morbid obesity, Leptin is a well known marker for obesity, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Leptin has also been implicated in a number of other processes including immune function, a 16kDa hormone that plays a key role in homeostasis, blood cell development, blood pressure, bone formation, but rather to a decrease in the amount of leptin that reaches and binds to the leptin receptors in the hypothalamus, fatty acid metabolism and reproductive function, glucose homeostasis, in energy intake and expenditure, leptin resistance is present in almost all obese humans, meaning that obesity is not necessarily due to a decrease in leptin, neuroendocrine function, the adaptive response to fasting, the amount of leptin in the circulation correlates with the amount of fat tissue, LEPTIN This item recognises human leptin, _x000D__x000D_ |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
LEPTIN |
| Short name: |
MOUSE Anti-HUMAN LEPTIN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens LEPTIN (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
8098 |
| Gene: |
OB |
More about : OB |
| Long gene name: |
leptin |
| Synonyms gene: |
OBS |
| Synonyms gene name: |
leptin (murine obesity homolog) leptin (obesity homolog, mouse) |
| Synonyms: |
LEP |
| Locus: |
7q32, 1 |
| Discovery year: |
1993-01-26 |
| Entrez gene record: |
3952 |
| Pubmed identfication: |
1686014 16932309 |
| Havana BLAST/BLAT: |
OTTHUMG00000157564 |