| Also known as: |
CD8 ALPHA |
| Other names: |
CD8 antigen, Lyt-2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-2, alpha chain, 1 lymphocyte differentiation antigen (AA at 100), T-cell surface glycoprotein CD8 alpha chain isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD8 ALPHA |
| Other gene names: |
BB154331, Cd8a, Ly-2, Ly-35, Ly-B, Lyt-2, Lyt-2, Lyt2, Cd8a |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
53-6, 7 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD8 is expressed on T-cells and exists either as a homodimer composed of two alpha chains, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD8 alpha chain specifically binds to class I MHC molecules, This antibody has also been used for depletion of CD8a<, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD8 functions as a co-receptor with the T-cell receptor and mediates efficient cell to cell interactions within the immune system, _x000D__x000D_The 53-6, cells, or a heterodimer composed of one alpha and one beta chain, the alpha chain of the CD8 antigen, +<, /sup>, 7 antibody has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2, CD8 ALPHA This item detects mouse CD8a, sup> |
| Form/Appearance: |
Phycoerythrin (RPE) Cy5 - liquid), RPE-CY5 (Purified IgG conjugated to R |
| Storage and shipping: |
DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of dispatch, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description: |
This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity, Cytotoxic T cells cluster differentiators for flow cytometry |
| Conjugation: |
5, Cy5 |
| Gene target: |
CD8 ALPHA:RPE |
| Short name: |
RAT ANTI MOUSE CD8 ALPHA:RPE- Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Cy5 |
| Alternative name: |
RAT antibody to MOUSE CD8 a:RPE-cyanine 5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10293 |
| Gene: |
RPE |
More about : RPE |
| Long gene name: |
ribulose-5-phosphate-3-epimerase |
| Locus: |
2q34 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
6120 |
| RefSeq identity: |
NM_006916 |
| Havana BLAST/BLAT: |
OTTHUMG00000154690 |