| Also known as: |
CD16 |
| Other names: |
Fc fragment of IgG, Fc fragment of IgG, Fc-gamma RIII, Fc-gamma RIII-beta, Fc-gamma RIIIb, Fc-gamma receptor IIIb (CD 16), FcR-10, FcRIII, FcRIIIb, IgG Fc receptor III-1, Low affinity immunoglobulin gamma Fc region receptor III-B, fc-gamma RIII, fc-gamma RIII-beta, fc-gamma RIIIb, igG Fc receptor III-1, low affinity IIIb, low affinity IIIb, low affinity immunoglobulin gamma Fc region receptor III-B, receptor (CD16b), receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-B isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD16 |
| Other gene names: |
CD16, CD16B, CD16b, FCG3, FCG3, FCGR3, FCGR3, FCGR3B, FCR-10, FCRIII, FCRIIIb, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, IGFR3, FCGR3B |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
DJ130c |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
, CD16 exists as a transmembranous form (Fc gammaRIIIA, CD16A is expressed by NK cells, CD16B exists as two allelic variants NA1 and NA2, DJ130c recognises all polymorphonuclear cells irrespective on their NA phenotype, In addition, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Studies show that the DJ130c antibody recognises an epitope in the first membrane-distal domain of CD16 and recognises both CD16A and CD16B, a 50-65kD cell surface molecule, and macrophages, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B), some T cells, whereas CD16B is primarily expressed by granulocytes, which is the low affinity receptor for IgG (FcR III), CD16 Recognises human CD16 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD16 |
| Short name: |
MOUSE Anti-HUMAN CD16 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD16 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
3620 |
| Gene: |
FCGR3B |
More about : FCGR3B |
| Long gene name: |
Fc fragment of IgG receptor IIIb |
| Synonyms gene: |
FCGR3 FCG3 |
| Synonyms gene name: |
Fc fragment of IgG, low affinity IIIb, low affinity IIIb, receptor (CD16b) , receptor for (CD16) Fc fragment of IgG |
| Synonyms: |
CD16 CD16b |
| Synonyms name: |
Fc gamma receptor IIIb |
| Locus: |
1q23, 3 |
| Discovery year: |
1991-08-21 |
| GenBank acession: |
J04162 |
| Entrez gene record: |
2215 |
| Pubmed identfication: |
2139735 |
| RefSeq identity: |
NM_000570 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000074099 |