| Also known as: |
CD18 |
| Other names: |
CD18/11B, CD18/11C, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, beta 2, beta 2 (complement component 3 receptor 3 and 4 subunit), cell surface adhesion glycoprotein LFA-1/CR3/P150, cell surface adhesion glycoproteins LFA-1/CR3/p150, complement receptor C3 beta-subunit, complement receptor C3 subunit beta, integrin, integrin beta chain, integrin beta-2, leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, 95 subunit beta, 95 subunit beta, 959 beta subunit precursor), integrin beta-2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD18 |
| Other gene names: |
CD18, CD18, ITGB2, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, MFI7, ITGB2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
MEM-148 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The epitope recognised by MEM-148 is also exposed during dissociation of the CD11/CD18 by low pH, This particular antibody might cross react with speacies outside of the listed ones, CD18 Recognises an epitope on the human CD18 molecule that is hidden in the CD11/CD18 heterodimer on resting cells |
| Form/Appearance: |
Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R |
| Storage and shipping: |
DO NOT FREEZE, Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD18 (ACTIVATION EPITOPE):RPE |
| Short name: |
MOUSE Anti-HUMAN CD18 (ACTIVATION EPITOPE):RPE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD18 (ACTIVATION EPITOPE):RPE (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
6155 |
| Gene: |
ITGB2 |
More about : ITGB2 |
| Long gene name: |
integrin subunit beta 2 |
| Synonyms gene: |
CD18 MFI7 |
| Synonyms gene name: |
beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin |
| Synonyms: |
LFA-1 MAC-1 |
| Synonyms name: |
complement component 3 receptor 3 and 4 subunit |
| Locus: |
21q22, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AK222505 |
| Entrez gene record: |
3689 |
| RefSeq identity: |
NM_000211 |
| Classification: |
Complement system Integrin beta subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000090257 |
| Locus Specific Databases: |
ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76 |