| Also known as: |
CD68 |
| Other names: |
CD68 antigen, Macrosialin, N/A, macrosialin, macrosialin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD68 |
| Other gene names: |
Cd68, Lamp4, N/A, Scard1, gp110, Cd68 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
FA-11 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Langerhans cells and at low levels by dendritic cells, MBS215395 does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation, Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, both are members of the lysosomal-associated membrane protein (lamp) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeabilisation, which is specifically expressed by tissue macrophages, CD68 Macrosialin is a heavily glycosylated transmembrane protein of 87-115kD |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), In vitro Assay, Western Blot (WB), Immunofluorescence (IF) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD68 |
| Short name: |
RAT ANTI MOUSE CD68 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD68 molecule (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD68 and IDBG-25923 and ENSG00000129226 and 968, CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960, Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514, GP110 and LAMP4 and SCARD1, Plasma membranes, this GO :0005765 and lysosomal membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0071310 and cellular response to organic substance and biological process, CD68 molecule |
| Identity: |
1693 |
| Gene: |
CD68 |
More about : CD68 |
| Long gene name: |
CD68 molecule |
| Synonyms gene name: |
CD68 antigen |
| Synonyms: |
SCARD1 macrosialin GP110 DKFZp686M18236 LAMP4 |
| Synonyms name: |
member 1 CD68 antigen macrophage antigen CD68 , scavenger receptor class D |
| Locus: |
17p13, 1 |
| Discovery year: |
1993-06-11 |
| GenBank acession: |
S57235 |
| Entrez gene record: |
968 |
| Pubmed identfication: |
9790779 |
| RefSeq identity: |
NM_001251 |
| Classification: |
CD molecules Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000108146 |