| Also known as: |
ESTROGEN RECEPTOR ALPHA |
| Other names: |
ER-alpha, ER-alpha, Estradiol receptor, Estrogen receptor, Nuclear receptor subfamily 3 group A member 1, estradiol receptor, estrogen nuclear receptor alpha, estrogen receptor, estrogen receptor 1, estrogen receptor alpha 3*, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha delta 3*, estrogen receptor alpha delta 3*, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*, estrogen receptor alpha delta 4*, nuclear receptor subfamily 3 group A member 1, 4, 4, 4, 5, 5, 5, 5, 5, 6, 6, 6, 6, 6, 7, 7*, 7*/654 isoform, 7*/819-2 isoform, 7*/822 isoform, 8*/901 isoform, 8*/941 isoform, estrogen receptor |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ER, ER, ESR, ESR, ESR1, ESRA, Era, NR3A1, NR3A1, ESR1 |
| Gene name synonims: |
ER, ER, ESR, ESR, ESR1, ESRA, Era, NR3A1, NR3A1, ESR1 |
| Other gene names: |
ER, ER, ESR, ESR, ESR1, ESRA, Era, NR3A1, NR3A1, ESR1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
6F11 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Approximately 75% to 80% of breast tumors have estrogen and/or progesterone receptors, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The detection of estrogen (ER) and progesterone (PR) receptors using immunohistochemical staining of formal fixed paraffin embedded (FFPE) tissue, This particular antibody might cross react with speacies outside of the listed ones, and the presence of these receptors helps determine both the patient's prognosis and the effectiveness of hormonal therapy , has gradually replaced ligand binding assays (LBA), to become the most common method for the determination of the ER/PR status of breast tumors, ESTROGEN RECEPTOR ALPHA Clone 6F11 recognises the human estrogen receptor alpha chain |
| Form/Appearance: |
S/N (Tissue Culture Supernatant - liquid) |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ESTROGEN RECEPTOR ALPHA |
| Short name: |
MOUSE Anti-HUMAN ESTROGEN RECEPTOR ALPHA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens ESTROGEN RECEPTOR a (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
3471 |
| Gene: |
ESRRA |
More about : ESRRA |
| Long gene name: |
estrogen related receptor alpha |
| Synonyms gene: |
ESRL1 |
| Synonyms: |
ERR1 ERRalpha NR3B1 ERRa |
| Locus: |
11q13, 1 |
| Discovery year: |
1997-04-25 |
| GenBank acession: |
X51416 L38487 |
| Entrez gene record: |
2101 |
| Pubmed identfication: |
3267207 |
| RefSeq identity: |
NM_004451 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150641 |