| Also known as: |
CD161b/c |
| Other names: |
CD161 antigen-like family member B, Killer cell lectin-like receptor subfamily B member 1B allele A, Ly-55b, Lymphocyte antigen 55b, N/A, N/A, NKR-P1 34, Natural killer cell surface protein NKR-P1B allele SJL/BALB, Killer cell lectin-like receptor subfamily B member 1B allele A |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD161b/c |
| Other gene names: |
Klrb1b, Ly-55b, Ly55b, N/A, NKR-P1B, Nkrp1b, N/A |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
PK136 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
-B and -C, -b, -c etc, Although previously thought to recognise only CD161c, CD161c expression itself is strain specific in mice, Engagement of CD161c has been reported to have activating function in NK cells, FVB/N and NZB, In the mouse the NKR-P1 family has three members, NKR-P1A, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antibody has also been used for <, The human protein has received the designation CD161, This item is useful for the identification of NK cells in selected strains of mice (positive on C57BL, This particular antibody might cross react with speacies outside of the listed ones, a cell surface glycoprotein encoded by members of the NKR-P1 gene family, activation of NK cells, and the mouse proteins have been referred to as CD161a, as only some CD161b positive strains are labelled by the antibody, but negative on AKR and BALB/c) and is also expressed by rare subsets of T cells and monocytes, but recognition of CD161b by PK136 appears to be even more complex, depletion of NK cells and <, recent data has shown that the PK136 antibody may also react with CD161b, whilst engagement of CD161b is inhibitory, whilst in the human only one member has been identified, /i>, /i>, 1 cell surface antigen, CD161b/c This item (clone PK136) recognises the mouse NK1, i>, i>, in vitro<, in vivo< |
| Form/Appearance: |
Biotin (Purified IgG conjugated to Biotin - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Biotinylated |
| Gene target: |
1, NK-1 |
| Short name: |
1 ANTIGEN: Antibody, MOUSE Anti-MOUSE NK-1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
1 protein:biotinilated (Antibody to), MOUSE antibody to-MOUSE NK-1 |
| Alternative technique: |
antibodies |