| Also known as: |
IL-6 |
| Other names: |
B-cell hybridoma growth factor, B-cell hybridoma growth factor, Interleukin HP-1, Interleukin-6, interleukin 6, interleukin HP-1, interleukin-6, interleukin-6 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
IL-6 |
| Other gene names: |
IL-6, Il-6, Il-6, Il6, Il6 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
6B4 IGH 54 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone 6B4 IGH 54 can be used to neutralise the activity of 50pg/ml of recombinant mouse IL-6 by >, _x000D__x000D_IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6R? chain (CD126) and the signal-transducing component gp130 (CD130), a multifunctional pro-inflammatory cytokine secreted by activated T cells, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue, but can also stimulate cells expressing gp130 through a soluble IL-6R, endothelial cells, fibroblasts and osteoblasts, macrophages, promote hybridoma growth, which acts as the principle inducer of the acute phase response in the liver, 95% in a functional assay, IL-6 This item is specific for mouse IL-6 (interleukin-6) |
| Form/Appearance: |
Azide Free (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, only, the antibody should be stored undiluted, Store the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
Functional Assay (FA), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
INTERLEUKIN-6: |
| Short name: |
RAT ANTI MOUSE INTERLEUKIN-6:Azide Free Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE Interleukin-6:Azide Free (Antibody to) |
| Alternative technique: |
antibodies |