| Also known as: |
IRF5 |
| Other names: |
IRF-5, Interferon regulatory factor 5, N/A, interferon regulatory factor 5, interferon regulatory factor 5, interferon regulatory factor 5 isoform b |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
IRF5 |
| Other gene names: |
IRF-5, IRF5, SLEB10, IRF5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
10T1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
, MCP-1 and IP-10, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies have shown that IRF5 can also regulate IFN gene transcription, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_The role of IRF3 and IRF7 as transcriptional mediators of virus- and IFN-induced signaling pathways is well documented, a 58kDa member of the IRF family which acts as a key regulator of interferon gene transcription, and has the ability to induce a wide range of chemokines involved in T-lymphocyte recruitment, and is expressed in B cells and dendritic cells, and is inducible by type I interferon (IFN) in most lymphoid cells, but appears to be more restricted in its cellular expression and range of viral stimuli, including RANTES, IRF5 This item recognises human interferon regulatory factor 5 (IRF5) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Paraffin (IHC), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
IRF5 |
| Short name: |
MOUSE Anti-HUMAN IRF5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens interferon regulatory factor 5 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051607 and defense response to virus and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, IRF5 and IDBG-40393 and ENSG00000128604 and 3663, IRF5 and IDBG-635292 and ENSBTAG00000004989 and 615340, Irf5 and IDBG-132026 and ENSMUSG00000029771 and 27056, SLEB10, nuclei, protein binding, this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000975 : regulatory region DNA binding, this GO :0000975 : regulatory region DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, interferon regulatory factor 5 |
| Identity: |
6120 |
| Gene: |
IRF5 |
More about : IRF5 |
| Long gene name: |
interferon regulatory factor 5 |
| Locus: |
7q32, 1 |
| Discovery year: |
1996-05-31 |
| Entrez gene record: |
3663 |
| RefSeq identity: |
NM_001098627 |
| Havana BLAST/BLAT: |
OTTHUMG00000158410 |