| Also known as: |
CD56 |
| Other names: |
N/A, NCAM, Neural cell adhesion molecule 1, antigen recognized by monoclonal antibody 5, neural cell adhesion molecule, neural cell adhesion molecule 1, neural cell adhesion molecule 1, 1H11, neural cell adhesion molecule 1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD56 |
| Other gene names: |
CD56, MSK39, N-CAM-1, NCAM, NCAM, NCAM-1, NCAM1, NCAM1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
123C3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Antibodies produced by clone 123C3 recognise the 140 and 180kD isoforms of the CD56 protein, CD56 is expressed in a range of tumours including tumours of the lung, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development, Neurons express the largest 180kD form, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid, The CD56 molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, This particular antibody might cross react with speacies outside of the listed ones, Three main isoforms of CD56 exist, _x000D__x000D_In neuronal tissues, natural killer cells and a subset of T cells in the peripheral blood, neural derived malignancies and natural killer cell lymphomas, otherwise known as CD56, while haemopoietic cells express the 140kD isoform, CD56 This item recognises human neural cell adhesion molecule (NCAM) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD56 |
| Short name: |
MOUSE Anti-HUMAN CD56 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD56 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
7656 |
| Gene: |
NCAM1 |
More about : NCAM1 |
| Long gene name: |
neural cell adhesion molecule 1 |
| Synonyms: |
NCAM CD56 |
| Locus: |
11q23, 2 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
4684 |
| RefSeq identity: |
NM_000615 |
| Classification: |
Fibronectin type III domain containing I-set domain containing CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000167196 |