| Also known as: |
PLVAP |
| Other names: |
MECA-32 antigen, MECA-32 antigen, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein, plasmalemma vesicle associated protein, plasmalemma vesicle protein 1, plasmalemma vesicle-associated protein, plasmalemma vesicle-associated protein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PLVAP |
| Other gene names: |
MECA32, PV-1, Plvap, Pv1, Pv1, Plvap |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
MECA-32 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
In adult and embryonic mice, In embryonic mice, PLVAP expression, PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_In humans, a 60kD protein which is otherwise known as MECA-32 and PV-1, as well as other cerebral disorders associated with blood-brain barrier disruption, cardiac and brain tissues, including glioblastoma and metastatic carcinoma, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated, such as acute ischemia, PLVAP This item recognises murine plasmalemma vesicle-associated protein (PLVAP) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
PLVAP |
| Short name: |
RAT ANTI MOUSE PLVAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE PLVAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13635 |
| Gene: |
PLVAP |
More about : PLVAP |
| Long gene name: |
plasmalemma vesicle associated protein |
| Synonyms: |
gp68 PV-1 PV1 FELS |
| Synonyms name: |
PV-1 protein , fenestrated-endothelial linked structure protein |
| Locus: |
19p13, 11 |
| Discovery year: |
2001-04-27 |
| GenBank acession: |
AF326591 |
| Entrez gene record: |
83483 |
| Pubmed identfication: |
11401446 |
| RefSeq identity: |
NM_031310 |
| Havana BLAST/BLAT: |
OTTHUMG00000182784 |