| Also known as: |
CD206 |
| Other names: |
C type 1, C type 1-like 1, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Macrophage mannose receptor 1, Macrophage mannose receptor 1-like protein 1, macrophage mannose receptor 1, macrophage mannose receptor 1-like protein 1, mannose receptor, mannose receptor, macrophage mannose receptor 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD206 |
| Other gene names: |
CD206, CLEC13D, CLEC13D, CLEC13DL, CLEC13DL, MMR, MMR, MRC1, MRC1L1, MRC1L1, bA541I19, 1, MRC1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
7-450 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The expression of CD206 is not restricted to macrophages, The widespread distribution and recognition of a wide range of antigens by macrophages, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), and is modulated by a range of factors including cytokines, but is also present on immature dendritic cells (DCs), endothelial cells, fungi and parasites, immunoglobulin receptors and pathogens, kidney mesangial cells, mycobacterium, otherwise known as macrophage mannose receptor (MMR), plays a key role in both innate and adaptive immunity, retinal pigment epithelium and tracheal smooth muscle cells, which mediates phagocytosis and endocytosis, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs), with CD206 able to bind to both gram-negative and gram-positive bacteria, yeasts, CD206 This item is specific for human CD206 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD206 |
| Short name: |
MOUSE Anti-HUMAN CD206 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD206 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
7228 |
| Gene: |
MRC1 |
More about : MRC1 |
| Long gene name: |
mannose receptor C-type 1 |
| Synonyms gene: |
MRC1L1 |
| Synonyms gene name: |
C type 1 , C type 1-like 1 mannose receptor, mannose receptor |
| Synonyms: |
CLEC13D CD206 bA541I19, 1 CLEC13DL |
| Synonyms name: |
macrophage mannose receptor |
| Locus: |
10p12, 33 |
| Discovery year: |
1992-07-30 |
| GenBank acession: |
J05550 |
| Entrez gene record: |
4360 |
| Pubmed identfication: |
1294118 |
| RefSeq identity: |
NM_002438 |
| Classification: |
CD molecules Scavenger receptors C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000174646 |