| known also as: |
Anti-Rabbit Polyclonal to Human Tuberin / TSC2 |
| known also as: |
Rabbit PAb to Human Tuberin / TSC2 |
| known also as: |
Lapin Polyclonal to Homo sapiens Tuberin / TSC2 |
| known also as: |
Tuberin / TSC2 |
| known also as: |
Human Tuberin, LAM, TSC2, TSC2, TSC4, Tuberin, Tuberous sclerosis 2, Tuberous sclerosis 2 protein, Anti-Tuberin / TSC2 Antibody (N-Terminus) IHC-plus |
| Other names: |
Tuberin, Tuberous sclerosis 2 protein, protein phosphatase 1, regulatory subunit 160, tuberin, tuberous sclerosis 2, tuberous sclerosis 2 protein, tuberin isoform 1 |
| Gene name: |
TSC2 |
| Other gene names: |
LAM, PPP1R160, TSC2, TSC4, TSC4, TSC2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
14 amino acid peptide from near the amino terminus of human TSC2 |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 02% sodium azide, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Store undiluted, avoid freeze thaw cycles, long term aliquot and store productone should be stored at -20 degrees Celsius, Short term Store productone at +4 degrees Celsius |
| Tested for:: |
Immunocytochemistry (ICC), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Tuberin / TSC2 |
| Short name: |
Anti- Tuberin / TSC2 |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Tuberin / tuberous sclerosis 2, antibody to-H |
| Alternative to gene target: |
14-3-3 protein binding, LAM and PPP1R160 and TSC4, TSC2 and IDBG-635000 and ENSBTAG00000020617 and 504985, TSC2 and IDBG-9819 and ENSG00000103197 and 7249, Tsc2 and IDBG-147651 and ENSMUSG00000002496 and 22084, nuclei, this GO :0001666 and response to hypoxia and biological process this GO :0001843 and neural tube closure and biological process this GO :0005096 and GTPase activator activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005901 and caveola and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006606 and protein import into nucleus and biological process this GO :0006897 and endocytosis and biological process this GO :0006953 and acute-phase response and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0008104 and protein localization and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0014067 and negative regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016192 and vesicle-mediated transport and biological process this GO :0019902 and phosphatase binding and molecular function this GO :0030030 and cell projection organization and biological process this GO :0030100 and regulation of endocytosis and biological process this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030425 and dendrite and cellular component this GO :0030426 and growth cone and cellular component this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0033596 and TSC1-TSC2 complex and cellular component this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043234 and protein complex and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045184 and establishment of protein localization and biological process this GO :0045792 and negative regulation of cell size and biological process this GO :0046626 and regulation of insulin receptor signaling pathway and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050918 and positive chemotaxis and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0071889 and 14-3-3 protein binding and molecular function, this GO :0005096 : GTPase activator activity, this GO :0005096 : GTPase activator activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0019902 : phosphatase binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity and also this GO :0071889 : 14-3-3 protein binding, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0019902 : phosphatase binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, this GO :0071889 : 14-3-3 protein binding, tuberous sclerosis 2 |
| Identity: |
12363 |
| Gene: |
TSC2 |
More about : TSC2 |
| Long gene name: |
tuberous sclerosis 2 |
| Synonyms gene: |
TSC4 |
| Synonyms: |
tuberin LAM PPP1R160 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 160 |
| Locus: |
16p13, 3 |
| Discovery year: |
1989-05-25 |
| GenBank acession: |
AB014460 |
| Entrez gene record: |
7249 |
| Pubmed identfication: |
1303246 7558029 |
| RefSeq identity: |
NM_000548 |
| Classification: |
Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000128745 |
| Locus Specific Databases: |
TSC2 Mutation Database Tuberous sclerosis database LRG_487 |